Detailed information NTG0112630

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: OU5_RS09180
• Genome accession: NZ_CP005960
• Coordinates: 2084825..2087059 (-)
• Length: 744 a.a.
• NCBI ID: WP_010461895.1
• Uniprot ID: A0A024E7W8
• Organism: Pseudomonas mandelii JR-1
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2079825..2092059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OU5_RS09145 (OU5_1816)	murB	2080201..2081220 (-)	1020	WP_010461881.1	UDP-N-acetylmuramate dehydrogenase	-
OU5_RS09150 (OU5_1817)	-	2081217..2081681 (-)	465	WP_010461884.1	low molecular weight protein-tyrosine-phosphatase	-
OU5_RS09155 (OU5_1818)	kdsB	2081681..2082445 (-)	765	WP_010461886.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
OU5_RS09160 (OU5_1819)	-	2082442..2082627 (-)	186	WP_010461887.1	Trm112 family protein	-
OU5_RS09165 (OU5_1820)	lpxK	2082653..2083663 (-)	1011	WP_010461890.1	tetraacyldisaccharide 4'-kinase	-
OU5_RS09170 (OU5_1821)	-	2083663..2084094 (-)	432	WP_010461891.1	ExbD/TolR family protein	-
OU5_RS09175 (OU5_1822)	exbB	2084091..2084726 (-)	636	WP_010461893.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
OU5_RS09180 (OU5_1823)	comA	2084825..2087059 (-)	2235	WP_010461895.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
OU5_RS09185 (OU5_1824)	-	2087195..2087713 (+)	519	WP_010461897.1	DUF2062 domain-containing protein	-
OU5_RS09190 (OU5_1825)	-	2087855..2088634 (-)	780	WP_010461900.1	ABC transporter permease	-
OU5_RS09195 (OU5_1826)	-	2088631..2089563 (-)	933	WP_010461902.1	ABC transporter ATP-binding protein	-
OU5_RS09200 (OU5_1827)	-	2089697..2090320 (-)	624	WP_010461904.1	glutathione S-transferase family protein	-
OU5_RS09205 (OU5_1828)	-	2090364..2091023 (-)	660	WP_010461906.1	transglutaminase-like domain-containing protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 81523.88 Da
• Isoelectric Point: 10.3061

>NTDB_id=112630 OU5_RS09180 WP_010461895.1 2084825..2087059(-) (comA) [Pseudomonas mandelii JR-1]
MRTGMMALALGLLALRFLPVLPPVWLWMLLPVVGLMLLPFRTHPLAFFLFGFSWACASAQWALDDRLSLTLDGETRRVEG
RVTGLPQNAEGVVRFELTDSQSRSTRLPRHLRLAWYDGPPVNSGERWRLAVKLKRPAGLLNLHAFDYDAWLLAQRIGATG
TVKDGHRLAAAQWAWRDSIRQQLQVVDAQGRTGALIALVLGDGGGLSREDWQVLQDTGTVHLLVISGQHIGLLAGLVYLL
IAGLARYGLWPSRLPWLPWACGLAFAAALGYGLLAGFEVPVRRACVMIGLVLLWRLRFRHLGAWWPLLLALNGVLLLDPL
ASLQPGFWLSFAAVAVLIFTFGGRLGPWRWWQTWTRAQWLIAIGLCPLLLILGLPISVSGPVANLLAVPWVSLVVLPPAL
LGTLLLPVPYVGEGLLWLAGGLVDLLFKGLALMAGRFPAWVPVAVPVWIWALGTLGAFLLLLPKGVPLRPLGWPLLLLLV
FPPRPMLAEGVAEVWQLDVGQGLAILVRTRHHTLLYDAGPRFGDFDLGERVVLPSLRKLGVSGIDLMLLSHADADHAGGA
RAVANGLPVARVLSGDPEALPAELRAEGCESGRQWTWDGVDFRLWQWTSAADSNQKSCVLQIEASGERLLLTGDIDAAAE
RALLDSPLAVPTDWLQSPHHGSRSSSSMALLVALQPRAVLISRGQGNSFGHPHPTVMARYQKRGMAIYDSATHGAIRLQL
GRFKPPWTMRLDRRFWRDPPPLGP

Nucleotide

• Length: 2235 bp

>NTDB_id=112630 OU5_RS09180 WP_010461895.1 2084825..2087059(-) (comA) [Pseudomonas mandelii JR-1]
ATGCGCACAGGGATGATGGCGCTGGCGTTGGGTTTGCTGGCCCTGCGTTTTTTACCGGTTTTACCGCCGGTCTGGTTATG
GATGTTGCTGCCGGTCGTGGGTTTGATGCTGTTGCCGTTTCGTACTCACCCGTTGGCGTTTTTTCTGTTCGGCTTCAGTT
GGGCGTGCGCGAGTGCGCAGTGGGCGCTGGATGATCGCCTGTCGCTGACGCTCGATGGCGAGACTCGTCGGGTCGAAGGT
CGGGTGACGGGCCTGCCGCAGAATGCCGAAGGGGTGGTGCGCTTCGAGTTGACCGACAGTCAGTCCCGAAGCACCCGGCT
GCCCCGGCATCTGCGCCTCGCCTGGTATGACGGACCGCCCGTCAACAGCGGCGAACGGTGGCGGCTGGCGGTCAAGTTGA
AGCGTCCTGCCGGGCTGCTCAATCTGCATGCCTTTGACTACGACGCCTGGTTGCTGGCACAACGCATCGGCGCTACCGGT
ACGGTCAAGGATGGCCATAGGCTGGCCGCCGCCCAATGGGCCTGGCGTGACAGCATTCGGCAGCAATTGCAGGTCGTCGA
TGCCCAAGGCCGGACGGGGGCGCTGATCGCATTGGTGTTGGGCGACGGCGGCGGGCTGAGTCGCGAGGACTGGCAAGTGC
TGCAAGACACCGGCACCGTGCATCTGCTGGTGATTTCCGGGCAGCACATCGGGTTGCTGGCGGGGCTGGTGTATCTGCTG
ATCGCCGGGCTGGCGCGCTATGGTCTGTGGCCGAGCCGTTTGCCCTGGCTGCCATGGGCCTGCGGACTGGCGTTTGCCGC
TGCGCTGGGTTACGGGTTGCTGGCCGGTTTTGAGGTGCCGGTGCGCCGGGCCTGCGTGATGATCGGTCTGGTGTTGTTGT
GGCGGCTAAGGTTTCGGCACCTTGGCGCCTGGTGGCCGCTGTTGCTGGCGCTCAATGGCGTTTTACTGCTCGACCCGCTG
GCGAGCCTGCAACCGGGGTTCTGGTTGTCCTTCGCAGCGGTGGCGGTGTTGATCTTCACCTTCGGTGGGCGTCTGGGGCC
GTGGCGTTGGTGGCAAACGTGGACCCGTGCGCAATGGCTGATCGCGATCGGACTGTGCCCATTGCTATTGATACTTGGCT
TGCCGATCAGCGTCAGCGGACCAGTGGCCAATTTGCTGGCGGTGCCTTGGGTCAGTCTGGTGGTATTGCCGCCAGCCTTG
CTCGGGACGTTGTTACTGCCCGTCCCTTATGTGGGCGAGGGGTTGCTGTGGCTGGCGGGCGGTCTGGTCGACCTGTTGTT
CAAGGGGCTGGCCTTGATGGCCGGACGATTCCCCGCCTGGGTGCCGGTCGCGGTGCCGGTGTGGATTTGGGCGCTCGGTA
CGCTGGGGGCCTTTCTTCTATTACTGCCTAAAGGGGTGCCGTTGCGCCCGTTGGGTTGGCCGCTGCTGCTGTTGCTGGTT
TTTCCACCTCGCCCGATGCTTGCCGAAGGCGTCGCCGAAGTCTGGCAGCTGGACGTCGGCCAAGGCCTGGCCATCCTGGT
GCGCACCCGCCATCACACCTTGTTGTATGACGCCGGGCCGCGTTTTGGCGATTTCGACCTCGGCGAGCGGGTGGTGCTGC
CGTCATTGCGCAAACTGGGCGTGTCCGGGATCGACCTGATGCTGCTCAGTCACGCCGACGCCGATCACGCCGGCGGTGCA
CGTGCGGTTGCCAACGGATTGCCGGTGGCGCGGGTCCTGAGCGGTGATCCCGAGGCGCTGCCAGCCGAATTGCGCGCCGA
AGGCTGTGAAAGCGGCCGGCAATGGACCTGGGACGGTGTGGACTTCCGTCTCTGGCAATGGACATCCGCCGCCGACAGCA
ATCAAAAATCCTGTGTCTTGCAGATCGAAGCCAGTGGCGAGCGATTGTTGCTGACCGGTGATATTGATGCGGCAGCCGAA
CGGGCATTGCTCGACAGTCCGCTTGCCGTGCCGACCGATTGGCTGCAATCGCCTCACCACGGCAGTCGCAGTTCCTCTTC
GATGGCGCTGCTCGTCGCGTTGCAACCCAGGGCAGTGCTGATTTCCCGGGGCCAAGGCAATTCCTTTGGCCACCCGCATC
CCACGGTCATGGCGCGCTATCAAAAACGCGGCATGGCGATCTACGACAGCGCCACCCACGGCGCCATTCGTCTGCAACTG
GGACGGTTCAAGCCGCCGTGGACGATGCGTCTGGATCGGCGTTTCTGGCGCGATCCGCCACCGTTGGGCCCATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (198-464)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-679)

• Domain of unknown function (DUF4131) (DUF4131) (23-166)

3D structure

• AlphaFold DB: A0A024E7W8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	63.408	96.237	0.61
comA	Ralstonia pseudosolanacearum GMI1000	33.495	100	0.371