Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   E0F39_RS11560 Genome accession   NZ_LR216060
Coordinates   2136953..2137615 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2131953..2142615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS11535 (SAMEA3713867_02176) - 2132104..2132370 (-) 267 WP_001278167.1 Veg family protein -
  E0F39_RS11540 (SAMEA3713867_02177) dnaB 2132372..2133724 (-) 1353 WP_050137283.1 replicative DNA helicase -
  E0F39_RS11545 (SAMEA3713867_02178) rplI 2133767..2134219 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  E0F39_RS11550 (SAMEA3713867_02179) - 2134216..2136189 (-) 1974 WP_001864876.1 DHH family phosphoesterase -
  E0F39_RS11555 (SAMEA3713867_02180) hpf 2136325..2136873 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  E0F39_RS11560 (SAMEA3713867_02181) comFC/cflB 2136953..2137615 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  E0F39_RS11565 (SAMEA3713867_02182) comFA/cflA 2137612..2138910 (-) 1299 WP_000867601.1 DEAD/DEAH box helicase Machinery gene
  E0F39_RS11570 (SAMEA3713867_02183) - 2138966..2139601 (+) 636 WP_000395739.1 YigZ family protein -
  E0F39_RS11575 (SAMEA3713867_02184) cysK 2139886..2140812 (+) 927 WP_000029873.1 cysteine synthase A -
  E0F39_RS11580 (SAMEA3713867_02185) - 2141011..2141493 (+) 483 Protein_2179 transposase -
  E0F39_RS11585 (SAMEA3713867_02186) tsf 2141561..2142601 (-) 1041 WP_000808063.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=1126230 E0F39_RS11560 WP_000649971.1 2136953..2137615(-) (comFC/cflB) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1126230 E0F39_RS11560 WP_000649971.1 2136953..2137615(-) (comFC/cflB) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCTTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment