Detailed information NTG1126162

Bioinformatically predicted

Overview

• Name: spo0J
• Type: Regulator
• Locus tag: E0F32_RS11185
• Genome accession: NZ_LR216050
• Coordinates: 2058424..2059182 (+)
• Length: 252 a.a.
• NCBI ID: WP_000410378.1
• Uniprot ID: A0A064C0A8
• Organism: Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2053424..2064182

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F32_RS11155 (SAMEA3431333_02093)	comE	2054021..2054773 (-)	753	WP_000866065.1	competence system response regulator transcription factor ComE	Regulator
E0F32_RS11160 (SAMEA3431333_02094)	comD/comD2	2054770..2056095 (-)	1326	WP_001842237.1	competence system sensor histidine kinase ComD	Regulator
E0F32_RS11165 (SAMEA3431333_02095)	comC/comC2	2056116..2056241 (-)	126	WP_000799694.1	competence-stimulating peptide ComC	Regulator
E0F32_RS11175 (SAMEA3431333_02097)	rlmH	2056523..2057002 (-)	480	WP_000695929.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
E0F32_RS11180 (SAMEA3431333_02098)	htrA	2057185..2058366 (+)	1182	WP_000681601.1	S1C family serine protease	Regulator
E0F32_RS11185 (SAMEA3431333_02099)	spo0J	2058424..2059182 (+)	759	WP_000410378.1	ParB/RepB/Spo0J family partition protein	Regulator
E0F32_RS11190 (SAMEA3431333_02100)	dnaA	2059395..2060756 (+)	1362	WP_000660618.1	chromosomal replication initiator protein DnaA	-
E0F32_RS11195 (SAMEA3431333_02101)	dnaN	2060915..2062051 (+)	1137	WP_000581157.1	DNA polymerase III subunit beta	-
E0F32_RS11200 (SAMEA3431333_02102)	-	2062116..2062310 (+)	195	WP_000285194.1	DUF951 domain-containing protein	-
E0F32_RS11205 (SAMEA3431333_02103)	ychF	2062394..2063509 (+)	1116	WP_001218707.1	redox-regulated ATPase YchF	-
E0F32_RS11210 (SAMEA3431333_02104)	pth	2063581..2064150 (+)	570	WP_000163930.1	aminoacyl-tRNA hydrolase	-

Sequence

Protein

• Length: 252 a.a.
• Molecular weight: 29153.50 Da
• Isoelectric Point: 9.0667

>NTDB_id=1126162 E0F32_RS11185 WP_000410378.1 2058424..2059182(+) (spo0J) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPIIVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQ
ISDQEMMVQSIIENLQRENLNPIEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLLGLDVEIKLSKKDSGKIIISFSN
QEEYSRIINSLK

Nucleotide

• Length: 759 bp

>NTDB_id=1126162 E0F32_RS11185 WP_000410378.1 2058424..2059182(+) (spo0J) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGGAAAAATTTGAAATGATTTCTATCACAGATATACAAAAAAATCCCTATCAACCCCGAAAAGAATTTGATAGAGAAAA
ACTAGATGAACTAGCACAGTCTATCAAAGAAAATGGGGTCATTCAACCGATTATTGTTCGTCAATCTCCTGTTATTGGTT
ATGAAATCCTTGCAGGAGAGAGACGCTATCGGGCTTCACTTTTAGCTGGTCTACGGTCTATCCCAGCTGTTGTTAAACAG
ATTTCAGACCAAGAGATGATGGTCCAGTCCATTATTGAAAATTTACAGAGAGAAAATTTAAACCCAATAGAAGAAGCACG
CGCCTATGAATCTCTCGTAGAGAAAGGATTCACCCATGCTGAAATTGCAGATAAGATGGGCAAGTCTCGTCCATATATCA
GCAACTCCATTCGTTTACTTTCCTTGCCAGAACAGATTCTTTCAGAAGTAGAAAATGGCAAACTATCACAAGCCCATGCG
CGTTCCCTAGTTGGGTTAAATAAGGAACAACAAGACTATTTCTTTCAACGGATTATAGAAGAAGATATTTCTGTAAGGAA
ATTAGAAGCTCTTCTGACAGAGAAAAAACAAAAGAAACAGCAAAAAACTAATCATTTCATACAAAATGAAGAAAAACAGT
TAAGAAAACTACTCGGATTAGATGTAGAAATTAAACTATCTAAAAAAGACAGTGGAAAAATCATTATTTCTTTTTCAAAT
CAAGAAGAATATAGTAGAATTATCAACAGCCTGAAATAA

Domains

Predicted by InterproScan.

• ParB/Sulfiredoxin domain (ParB_N) (6-94)

• HTH domain found in ParB protein (HTH_ParB) (144-192)

3D structure

• AlphaFold DB: A0A064C0A8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0J	Streptococcus mutans UA159	50.593	100	0.508