Detailed information NTG0112445

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: LA24_RS07460
• Genome accession: NZ_CP009419
• Coordinates: 1396356..1397387 (+)
• Length: 343 a.a.
• NCBI ID: WP_002220958.1
• Uniprot ID: Q9JZ86
• Organism: Neisseria meningitidis M7124
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1391356..1402387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA24_RS07440 (LA24_07840)	-	1392266..1392640 (-)	375	WP_002220962.1	arsenate reductase	-
LA24_RS07445 (LA24_07855)	-	1392790..1394418 (+)	1629	WP_002224512.1	ABC-F family ATPase	-
LA24_RS07450 (LA24_07860)	-	1394490..1395743 (+)	1254	WP_002248057.1	multifunctional CCA addition/repair protein	-
LA24_RS07455 (LA24_07870)	-	1395966..1396274 (+)	309	WP_002217140.1	hypothetical protein	-
LA24_RS07460 (LA24_07875)	ruvB	1396356..1397387 (+)	1032	WP_002220958.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LA24_RS07465 (LA24_07880)	rpe	1397410..1398138 (-)	729	WP_002219237.1	ribulose-phosphate 3-epimerase	-
LA24_RS07470 (LA24_07885)	-	1398284..1398718 (+)	435	WP_002213489.1	Spy/CpxP family protein refolding chaperone	-
LA24_RS07480 (LA24_07895)	-	1398731..1399594 (-)	864	Protein_1415	ATP-binding protein	-
LA24_RS14240 (LA24_07900)	-	1399602..1400219 (-)	618	WP_002217135.1	riboflavin synthase	-
LA24_RS14245 (LA24_07905)	-	1400382..1400997 (-)	616	Protein_1417	molybdenum cofactor guanylyltransferase	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37660.13 Da
• Isoelectric Point: 5.0462

>NTDB_id=112445 LA24_RS07460 WP_002220958.1 1396356..1397387(+) (ruvB) [Neisseria meningitidis M7124]
MLQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQDKAKEQLAIFIQAAKKRGEALDHVLLFGPPGLGKTTL
AHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFIDEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKID
LPPFTLIGATTRAGMLTNPLRDRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMSEEGAEEIAKRSRGTPRIANRLLRRVR
DFADVKNNGTIDGGIADAALSMLDVDAQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGESTDTIEDVIEPYLIQQGFL
QRTPRGRMATERAYLHFGLPVEK

Nucleotide

• Length: 1032 bp

>NTDB_id=112445 LA24_RS07460 WP_002220958.1 1396356..1397387(+) (ruvB) [Neisseria meningitidis M7124]
ATGCTGCAAACCGACAACCTGACCGCCGCGCAACCGCAACGCATCGTTGCCGCCCAAACCGCCTCCGCACAGGAAGAACT
GCTCGAACGCGCCCTCCGCCCCAAAACGCTGGACGACTACATCGGGCAAGACAAAGCCAAAGAACAGCTTGCCATTTTCA
TCCAAGCCGCCAAAAAACGCGGCGAAGCACTCGACCACGTTTTGCTCTTCGGCCCGCCCGGACTGGGCAAAACCACACTG
GCGCACATCATCGCCAAAGAATTGGGCGTAAATTTGCGCCAAACCAGCGGCCCCGTCCTCGAACGCGCAGGCGACCTCGC
CGCCCTTTTGACCAACCTTGATCCGCACGATGTATTGTTCATCGACGAAATCCACCGCCTCAGCCCTGTTGTCGAAGAAA
TCCTCTATCCCGCGCTCGAAGACTACCGGCTCGACATTATGATAGGCGAAGGACCCGCCGCCCGTTCCGTCAAAATCGAC
CTGCCGCCCTTCACGCTCATCGGCGCGACCACCCGCGCCGGTATGCTGACCAATCCGTTGCGCGACCGCTTCGGCATCGT
CTCCCGCCTTGAGTTTTACGAAAACCGAGACCTTACCACCATCGTCAGCCGTTCGGCACAACTGTTGCAGCTCGATATGT
CCGAAGAAGGCGCGGAAGAAATCGCCAAACGCAGCCGCGGTACGCCGCGCATCGCCAACCGCCTGTTGCGACGCGTGCGC
GATTTCGCCGACGTGAAAAACAACGGCACAATCGACGGCGGCATCGCCGATGCCGCTTTAAGTATGCTGGACGTGGACGC
GCAGGGGCTGGACGTGATGGACAGGAAATTTCTCGAAGCCGTTTTGCACAAATTCGGCGGCGGCCCGGTCGGTTTGGACA
ATGTTGCCGCCGCCATCGGCGAATCTACAGACACCATCGAAGACGTTATCGAACCCTACCTTATCCAACAAGGCTTCCTG
CAACGCACCCCGCGCGGCAGGATGGCGACCGAACGCGCCTACCTGCATTTCGGGCTGCCCGTCGAAAAATAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (268-337)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (32-190)

• RuvB AAA lid domain (AAA_lid_4) (193-266)

3D structure

• AlphaFold DB: Q9JZ86

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae TIGR4	63.376	91.545	0.58
ruvB	Streptococcus pneumoniae R6	63.376	91.545	0.58
ruvB	Streptococcus pneumoniae D39	63.376	91.545	0.58
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.55	95.335	0.577
ruvB	Helicobacter pylori 26695	57.508	91.254	0.525
ruvB	Synechocystis sp. PCC 6803	54.573	95.627	0.522