Detailed information NTG1123873

Bioinformatically predicted

Overview

• Name: dsbA2
• Type: Machinery gene
• Locus tag: EL310_RS09470
• Genome accession: NZ_LR134522
• Coordinates: 1612082..1612777 (-)
• Length: 231 a.a.
• NCBI ID: WP_002215704.1
• Uniprot ID: Q7DDR6
• Organism: Neisseria meningitidis strain NCTC3372
• Function: DNA binding and uptake; interact with PilQ (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1603092..1613606	1612082..1612777	within	0

Gene organization within MGE regions

Location: 1603092..1613606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL310_RS09420 (NCTC3372_01589)	comE	1603092..1603556 (-)	465	WP_010981251.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL310_RS09460 (NCTC3372_01595)	-	1609354..1610160 (-)	807	WP_002245849.1	inner membrane protein YpjD	-
EL310_RS09465 (NCTC3372_01596)	ffh	1610381..1611751 (+)	1371	WP_002245848.1	signal recognition particle protein	-
EL310_RS09470 (NCTC3372_01597)	dsbA2	1612082..1612777 (-)	696	WP_002215704.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
EL310_RS09475 (NCTC3372_01598)	-	1613055..1613606 (-)	552	WP_002249239.1	NYN domain-containing protein	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 25419.90 Da
• Isoelectric Point: 5.1502

>NTDB_id=1123873 EL310_RS09470 WP_002215704.1 1612082..1612777(-) (dsbA2) [Neisseria meningitidis strain NCTC3372]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide

• Length: 696 bp

>NTDB_id=1123873 EL310_RS09470 WP_002215704.1 1612082..1612777(-) (dsbA2) [Neisseria meningitidis strain NCTC3372]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCCGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

• Thioredoxin (Thioredoxin_4) (65-212)

3D structure

• AlphaFold DB: Q7DDR6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dsbA2	Neisseria meningitidis MC58	100	100	1
dsbA1	Neisseria meningitidis MC58	71.245	100	0.719