Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   EL267_RS10730 Genome accession   NZ_LR134520
Coordinates   2053395..2054306 (-) Length   303 a.a.
NCBI ID   WP_126419164.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC13947     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2048395..2059306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL267_RS10710 (NCTC13947_02122) - 2049349..2051127 (-) 1779 WP_001220909.1 acyltransferase family protein -
  EL267_RS10715 (NCTC13947_02123) - 2051124..2051504 (-) 381 WP_000787700.1 membrane protein -
  EL267_RS10720 (NCTC13947_02124) - 2051511..2051948 (-) 438 WP_000754813.1 low molecular weight protein-tyrosine-phosphatase -
  EL267_RS10725 (NCTC13947_02125) ruvB 2052100..2053098 (-) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB -
  EL267_RS10730 (NCTC13947_02126) comR 2053395..2054306 (-) 912 WP_126419164.1 helix-turn-helix domain-containing protein Regulator
  EL267_RS10735 (NCTC13947_02127) purB 2054459..2055757 (-) 1299 WP_000572887.1 adenylosuccinate lyase -
  EL267_RS10740 (NCTC13947_02128) - 2055782..2057173 (-) 1392 WP_001079802.1 hypothetical protein -
  EL267_RS10745 (NCTC13947_02129) purK 2057227..2058318 (-) 1092 WP_001084005.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  EL267_RS10750 (NCTC13947_02130) purE 2058305..2058793 (-) 489 WP_001182532.1 5-(carboxyamino)imidazole ribonucleotide mutase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35642.06 Da        Isoelectric Point: 5.6370

>NTDB_id=1123842 EL267_RS10730 WP_126419164.1 2053395..2054306(-) (comR) [Streptococcus agalactiae strain NCTC13947]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YLILRIPTYADAERLKLRECQFDHTFEEFYDNLPEDECLAIDSLQAKFEVYQTGDINFGVEVLCECFDKVKYKEKYTLND
LIIIDLFLTCAVVSKFNNRAFTKEVFQTICKTLISQNHKLTAEDLFWFNHVLLNCVFVGLCLNSEECLAEMLEVSRQTMV
STHDFHKMPLYFMYQWKYFITIDNDIKSAENAYQQSIMFSKMIDDKHLIKKLELEWQEDITGH

Nucleotide


Download         Length: 912 bp        

>NTDB_id=1123842 EL267_RS10730 WP_126419164.1 2053395..2054306(-) (comR) [Streptococcus agalactiae strain NCTC13947]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TATTTGATTTTAAGAATTCCAACTTATGCAGATGCTGAACGATTAAAATTAAGAGAATGTCAGTTTGATCATACTTTCGA
AGAATTCTATGATAATCTTCCAGAAGACGAGTGCTTAGCAATTGACAGTTTACAAGCTAAATTTGAAGTCTATCAAACAG
GAGACATTAATTTTGGTGTGGAGGTTTTATGCGAATGCTTTGATAAAGTAAAATATAAAGAAAAATATACTCTTAATGAT
TTGATTATCATAGATTTGTTTTTAACTTGTGCAGTTGTATCTAAATTTAACAATAGAGCATTTACTAAAGAAGTATTTCA
AACTATATGTAAAACTTTGATAAGTCAGAACCACAAACTTACAGCAGAAGATTTGTTTTGGTTTAATCATGTACTCCTGA
ATTGTGTATTTGTTGGACTTTGTTTAAATAGTGAAGAGTGTCTTGCAGAAATGTTAGAAGTTAGCCGACAAACGATGGTG
TCAACACATGATTTTCATAAAATGCCTTTATATTTTATGTACCAATGGAAATACTTCATTACAATTGACAATGATATAAA
GTCTGCAGAAAATGCTTACCAACAATCAATTATGTTTTCAAAAATGATTGATGACAAGCATCTAATTAAAAAATTAGAAT
TGGAGTGGCAAGAAGATATAACAGGACATTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(10-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

52.333

99.01

0.518
  comR Streptococcus mutans UA159

44.482

98.68

0.439
  comR Streptococcus pyogenes MGAS8232

42.574

100

0.426
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

43.986

96.04

0.422

Multiple sequence alignment