Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL267_RS05945 Genome accession   NZ_LR134520
Coordinates   1135668..1136981 (+) Length   437 a.a.
NCBI ID   WP_000042576.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC13947     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1130668..1141981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL267_RS05925 (NCTC13947_01168) pstB 1130702..1131460 (+) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -
  EL267_RS05930 (NCTC13947_01169) phoU 1131494..1132147 (+) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  EL267_RS05935 (NCTC13947_01170) - 1132293..1134842 (+) 2550 WP_121205169.1 M1 family metallopeptidase -
  EL267_RS05940 (NCTC13947_01171) ciaR 1135004..1135684 (+) 681 WP_000590620.1 response regulator transcription factor Regulator
  EL267_RS05945 (NCTC13947_01172) ciaH 1135668..1136981 (+) 1314 WP_000042576.1 sensor histidine kinase Regulator
  EL267_RS05950 (NCTC13947_01173) - 1137070..1137402 (+) 333 WP_000402075.1 putative DNA-binding protein -
  EL267_RS05955 (NCTC13947_01174) ffh 1137420..1138985 (+) 1566 WP_000863593.1 signal recognition particle protein -
  EL267_RS05960 (NCTC13947_01175) - 1139052..1139738 (+) 687 WP_000280304.1 SatD family protein -
  EL267_RS05965 (NCTC13947_01176) - 1139728..1140501 (+) 774 WP_000622396.1 DUF3307 domain-containing protein -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49678.12 Da        Isoelectric Point: 9.4961

>NTDB_id=1123809 EL267_RS05945 WP_000042576.1 1135668..1136981(+) (ciaH) [Streptococcus agalactiae strain NCTC13947]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=1123809 EL267_RS05945 WP_000042576.1 1135668..1136981(+) (ciaH) [Streptococcus agalactiae strain NCTC13947]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATTTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATTCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGATTTGGCCTC
GGTCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.373

98.169

0.593
  ciaH Streptococcus pneumoniae Rx1

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae D39

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae R6

52.143

96.11

0.501
  ciaH Streptococcus pneumoniae TIGR4

52.143

96.11

0.501

Multiple sequence alignment