Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   EL264_RS00960 Genome accession   NZ_LR134519
Coordinates   195475..196218 (+) Length   247 a.a.
NCBI ID   WP_126473961.1    Uniprot ID   -
Organism   Helicobacter pylori strain NCTC12823     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 190475..201218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL264_RS00935 (NCTC12823_00189) panD 192633..192986 (+) 354 WP_024368743.1 aspartate 1-decarboxylase -
  EL264_RS00940 (NCTC12823_00190) - 192989..193291 (+) 303 WP_000347928.1 YbaB/EbfC family nucleoid-associated protein -
  EL264_RS00945 (NCTC12823_00191) - 193291..194286 (+) 996 WP_126474832.1 PDZ domain-containing protein -
  EL264_RS00950 (NCTC12823_00192) comB6 194294..195349 (+) 1056 WP_126474831.1 P-type conjugative transfer protein TrbL Machinery gene
  EL264_RS00955 (NCTC12823_00193) comB7 195365..195478 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  EL264_RS00960 (NCTC12823_00194) comB8 195475..196218 (+) 744 WP_126473961.1 type IV secretion system protein Machinery gene
  EL264_RS00965 (NCTC12823_00195) comB9 196218..197201 (+) 984 WP_126473963.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  EL264_RS00970 (NCTC12823_00196) comB10 197194..198324 (+) 1131 WP_126473965.1 DNA type IV secretion system protein ComB10 Machinery gene
  EL264_RS00975 (NCTC12823_00197) - 198394..199806 (+) 1413 WP_126473967.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  EL264_RS00980 (NCTC12823_00198) gmd 199836..200981 (+) 1146 WP_096468567.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28689.91 Da        Isoelectric Point: 8.3165

>NTDB_id=1123779 EL264_RS00960 WP_126473961.1 195475..196218(+) (comB8) [Helicobacter pylori strain NCTC12823]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSHYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=1123779 EL264_RS00960 WP_126473961.1 195475..196218(+) (comB8) [Helicobacter pylori strain NCTC12823]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCATCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGATTGGAAAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTATCTTAGCGATCGTGTTAATCAGTCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGTATTAATCGCATTGACGATAAATCGCACT
ATGAATTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCACAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAACAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

98.381

100

0.984

Multiple sequence alignment