Detailed information NTG1122518

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL201_RS13490
• Genome accession: NZ_LR134380
• Coordinates: 2993712..2994797 (+)
• Length: 361 a.a.
• NCBI ID: WP_027222750.1
• Uniprot ID: A0AAX2J015
• Organism: Legionella pneumophila subsp. pascullei strain NCTC12273
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2988712..2999797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL201_RS13465 (NCTC12273_02697)	-	2989105..2989854 (-)	750	WP_027222745.1	CPBP family glutamic-type intramembrane protease	-
EL201_RS13470 (NCTC12273_02698)	rsmB	2989851..2991134 (-)	1284	WP_027222746.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
EL201_RS13475 (NCTC12273_02699)	fmt	2991131..2992075 (-)	945	WP_027222747.1	methionyl-tRNA formyltransferase	-
EL201_RS13480 (NCTC12273_02700)	def	2992072..2992584 (-)	513	WP_027222748.1	peptide deformylase	-
EL201_RS13485 (NCTC12273_02701)	-	2992678..2993715 (+)	1038	WP_027222749.1	LysM peptidoglycan-binding domain-containing protein	-
EL201_RS13490 (NCTC12273_02702)	dprA	2993712..2994797 (+)	1086	WP_027222750.1	DNA-processing protein DprA	Machinery gene
EL201_RS13495 (NCTC12273_02703)	-	2994787..2995224 (+)	438	WP_027222751.1	DUF494 family protein	-
EL201_RS13500 (NCTC12273_02704)	topA	2995304..2997583 (+)	2280	WP_027222752.1	type I DNA topoisomerase	-
EL201_RS13505 (NCTC12273_02705)	-	2997685..2999658 (-)	1974	WP_027222753.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39569.90 Da
• Isoelectric Point: 7.7923

>NTDB_id=1122518 EL201_RS13490 WP_027222750.1 2993712..2994797(+) (dprA) [Legionella pneumophila subsp. pascullei strain NCTC12273]
MSNLQPLLALNRMKKIGPRTVLKLQKRWPDLNLMFQLSRAELEQAGMPPWLAQTIKNFDQDFIKADLDWLNSSENHHIVT
WDSPYYPALLKEIADPPFILYAKGELSALTQTSLAIVGSRNASVTGNENARVFSKEISRYGVTIVSGLALGIDAHAHLGC
LEAGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMAVEQNRDVLAIPGSIHNPLARGCHHLLQQGAKLVTSVTDVLDELKIEHHQIASNKPIFSLASGKENLVKFIGFETTAI
DQIIVRSGYSMEQVTSGLAELELKGAVMAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=1122518 EL201_RS13490 WP_027222750.1 2993712..2994797(+) (dprA) [Legionella pneumophila subsp. pascullei strain NCTC12273]
ATGAGTAATCTGCAACCCCTCCTCGCCTTAAACAGGATGAAAAAAATTGGCCCCAGGACTGTATTAAAACTACAAAAAAG
ATGGCCTGATTTAAACCTTATGTTTCAACTGTCCCGCGCTGAACTGGAACAAGCTGGCATGCCGCCTTGGCTGGCACAAA
CCATAAAAAATTTTGACCAAGACTTTATAAAAGCTGATTTAGACTGGCTAAATTCATCAGAAAATCATCATATTGTAACT
TGGGACTCCCCATATTATCCTGCATTACTCAAAGAAATCGCGGATCCTCCCTTTATTTTATATGCCAAAGGTGAACTTTC
TGCTTTGACACAAACTAGTCTGGCAATTGTTGGAAGTCGCAATGCTTCTGTGACAGGGAATGAAAATGCTCGGGTATTCT
CCAAAGAGATTTCCAGGTATGGGGTAACCATAGTGAGTGGTTTGGCCTTAGGAATTGATGCCCATGCCCATTTAGGTTGT
CTGGAAGCAGGTGGCAAAACAATAGCGGTTTTAGGTACGGGAATTGATTGCATCTATCCGCGTCGACATTTAAAATTGGC
CGAGCAAATTACCGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCGCCAATCGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCGGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTGTGGAACAAAATAGAGATGTATTGGCTATTCCCGGTTCGATTCATAACCCTTTAGCCAGGGGCTGCCACCA
CTTATTGCAACAAGGTGCAAAATTAGTAACCTCAGTGACTGATGTTCTCGATGAGCTAAAAATAGAGCACCATCAGATCG
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACGGCTATC
GATCAAATCATTGTTCGTAGCGGATATAGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
TATGGCAGTTCCCGGTGGCTATATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (299-353)

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	92.244	100	0.922
dprA	Vibrio cholerae strain A1552	42.895	100	0.443
dprA	Vibrio campbellii strain DS40M4	44.167	99.723	0.44
dprA	Glaesserella parasuis strain SC1401	38.133	100	0.396
dprA	Haemophilus influenzae Rd KW20	45.455	82.271	0.374