Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EL239_RS05805 Genome accession   NZ_LR134374
Coordinates   1336736..1337380 (-) Length   214 a.a.
NCBI ID   WP_172597055.1    Uniprot ID   -
Organism   Legionella spiritensis strain NCTC12082     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1331736..1342380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL239_RS05790 (NCTC12082_01177) - 1332774..1333346 (-) 573 WP_126338758.1 heme NO-binding domain-containing protein -
  EL239_RS05795 (NCTC12082_01178) - 1333502..1334434 (-) 933 WP_126338759.1 hypothetical protein -
  EL239_RS05800 (NCTC12082_01179) uvrC 1334609..1336477 (-) 1869 WP_126338760.1 excinuclease ABC subunit UvrC -
  EL239_RS05805 (NCTC12082_01180) letA 1336736..1337380 (-) 645 WP_172597055.1 two-component system response regulator LetA Regulator
  EL239_RS05810 (NCTC12082_01181) phhA 1337466..1338284 (-) 819 WP_126338761.1 phenylalanine 4-monooxygenase -
  EL239_RS05815 (NCTC12082_01182) - 1338336..1339583 (-) 1248 WP_126338762.1 sterol desaturase family protein -
  EL239_RS05820 (NCTC12082_01183) bioC 1339778..1340626 (-) 849 WP_126338763.1 malonyl-ACP O-methyltransferase BioC -
  EL239_RS05825 (NCTC12082_01184) comFC 1340666..1341382 (+) 717 WP_232001743.1 ComF family protein Machinery gene

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24002.20 Da        Isoelectric Point: 6.5008

>NTDB_id=1122402 EL239_RS05805 WP_172597055.1 1336736..1337380(-) (letA) [Legionella spiritensis strain NCTC12082]
MIKVLIVDDHALVRMGIRRLLEDLPDMDVVAEAESGEQALALVKSHKPDVVLLDMKMPGIDGWEVTRRLKKSNPQIRIIA
VTAICAEPLPSRILQLGAMGYLTKESGVQEMAAAIRKVAKGEKYLSAEIAQKMAINSLEAVEESPFDRLSEREMQVMFMI
TSGMTVHDIAERLFLSTKTINGYRYRMFDKLGIKNDVELTFLAMKHSVIEKPSD

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1122402 EL239_RS05805 WP_172597055.1 1336736..1337380(-) (letA) [Legionella spiritensis strain NCTC12082]
TTGATAAAAGTACTAATTGTTGATGACCATGCCTTGGTAAGAATGGGTATTCGACGATTACTGGAAGATTTGCCGGATAT
GGATGTGGTTGCCGAAGCGGAAAGCGGAGAGCAGGCTTTAGCTTTGGTTAAATCCCATAAACCCGATGTTGTTCTTCTTG
ATATGAAAATGCCTGGTATTGATGGCTGGGAAGTCACTCGTCGTTTAAAAAAATCAAATCCGCAAATCCGGATCATCGCT
GTTACGGCGATTTGTGCCGAGCCGTTGCCCAGTCGTATTCTGCAGTTAGGAGCCATGGGGTATTTGACCAAGGAATCCGG
CGTACAGGAAATGGCGGCGGCTATCCGTAAGGTGGCGAAGGGTGAGAAATACCTTAGTGCCGAGATTGCTCAAAAAATGG
CTATTAACAGTCTGGAGGCCGTTGAGGAATCGCCGTTTGATCGTTTGTCCGAACGCGAAATGCAAGTGATGTTTATGATT
ACCAGCGGCATGACGGTTCATGATATTGCCGAGCGTTTATTTTTGAGTACCAAGACTATCAATGGCTACCGTTATCGCAT
GTTTGATAAATTAGGTATCAAAAACGACGTGGAACTCACGTTTTTGGCTATGAAGCATAGCGTGATCGAAAAACCGAGTG
ATTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-203)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

84.112

100

0.841
  letA Legionella pneumophila strain ERS1305867

84.112

100

0.841

Multiple sequence alignment