Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EL148_RS06880 Genome accession   NZ_LR134364
Coordinates   1430016..1431209 (-) Length   397 a.a.
NCBI ID   WP_064081941.1    Uniprot ID   -
Organism   [Haemophilus] ducreyi strain NCTC11483     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1425016..1436209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL148_RS06850 (NCTC11483_01438) lptE 1426983..1427480 (+) 498 WP_074647595.1 LPS assembly lipoprotein LptE -
  EL148_RS06855 (NCTC11483_01439) holA 1427486..1428511 (+) 1026 WP_074647593.1 DNA polymerase III subunit delta -
  EL148_RS06860 (NCTC11483_01440) yacG 1428545..1428733 (-) 189 WP_064081939.1 DNA gyrase inhibitor YacG -
  EL148_RS06865 (NCTC11483_01441) coaE 1428736..1429353 (-) 618 WP_064081940.1 dephospho-CoA kinase -
  EL148_RS06870 (NCTC11483_01442) - 1429371..1429754 (-) 384 WP_335673639.1 prepilin peptidase -
  EL148_RS06875 (NCTC11483_01443) - 1429747..1430016 (-) 270 WP_078179334.1 hypothetical protein -
  EL148_RS06880 (NCTC11483_01444) pilC 1430016..1431209 (-) 1194 WP_064081941.1 type II secretion system F family protein Machinery gene
  EL148_RS06885 (NCTC11483_01445) pilB 1431193..1432587 (-) 1395 WP_064081942.1 GspE/PulE family protein Machinery gene
  EL148_RS06890 (NCTC11483_01446) pilA 1432599..1433045 (-) 447 WP_064081943.1 pilin Machinery gene
  EL148_RS06895 (NCTC11483_01447) radA 1433239..1434618 (+) 1380 WP_064081944.1 DNA repair protein RadA -
  EL148_RS06900 (NCTC11483_01448) - 1434685..1434900 (-) 216 WP_010945033.1 YgjV family protein -
  EL148_RS06905 (NCTC11483_01449) - 1435022..1435507 (-) 486 WP_064081945.1 dihydrofolate reductase -

Sequence

Protein


Download         Length: 397 a.a.        Molecular weight: 45709.40 Da        Isoelectric Point: 10.1709

>NTDB_id=1122303 EL148_RS06880 WP_064081941.1 1430016..1431209(-) (pilC) [[Haemophilus] ducreyi strain NCTC11483]
MLKIYEFHWRAFNRFNQRQKGKSLAKSHDELEQRLLAKGYSNIHIQRDFILVRKPKSEQITQLINQLAMLLNASVPLKQS
LVMVLENVHNIKLYLWLYEIITLLEAGHTFSASLTKMNVYLTKQEIQLIKMGEQSGRLAIMLDNIAKVRTQSQKLANKVK
KIMFYPAIILAVSISVLIGLLLFIVPQFEDLYRNKDQSLPFITQLLFQLSNFLQQYAFILFIGGLFSGIVSYFLAKKRLF
WRTLRSRLLNHMPGFQQIIKDARIIFFSQNLALMLNAHIHLDATLKAFLSEHRQDPVLHQEILSILSLLKQGYKFSEGLN
PTVFTSQVVQMMAIGEQSGNLAKMCMCISQLYQQKLDYQIDLFAQLLEPVLMLVIGIIVGTILIGIYLPIFDMGALV

Nucleotide


Download         Length: 1194 bp        

>NTDB_id=1122303 EL148_RS06880 WP_064081941.1 1430016..1431209(-) (pilC) [[Haemophilus] ducreyi strain NCTC11483]
ATGCTGAAAATATATGAATTTCATTGGCGGGCTTTTAATCGTTTTAATCAACGGCAAAAAGGTAAATCTCTGGCCAAAAG
TCACGATGAATTAGAACAACGGCTATTAGCTAAAGGCTATTCAAATATCCATATTCAACGTGATTTTATTTTAGTTAGGA
AACCCAAAAGCGAACAAATCACTCAATTAATTAATCAGTTAGCTATGTTATTGAATGCCTCGGTTCCATTAAAACAATCG
CTGGTGATGGTATTAGAAAACGTACATAATATTAAATTATATTTATGGTTATATGAAATTATTACGCTGTTAGAAGCGGG
GCATACTTTTTCAGCCAGTCTCACTAAAATGAACGTTTATTTGACTAAGCAAGAAATTCAGTTAATTAAGATGGGAGAAC
AGAGTGGGCGTTTAGCCATTATGCTAGATAACATTGCAAAAGTACGTACTCAATCACAGAAATTAGCTAATAAAGTAAAG
AAAATTATGTTTTATCCGGCGATTATTTTAGCCGTATCAATTAGTGTATTAATTGGATTGTTATTATTTATTGTGCCTCA
ATTTGAAGATCTTTATCGTAACAAAGATCAGTCACTGCCTTTTATTACCCAATTATTATTTCAGTTATCGAATTTTCTTC
AACAATATGCATTTATTTTATTCATCGGCGGCCTATTTAGCGGTATTGTTAGCTATTTTTTAGCGAAAAAGAGGCTTTTT
TGGCGTACCTTAAGATCGCGTTTATTAAATCATATGCCAGGGTTTCAGCAAATTATTAAAGATGCTCGAATTATTTTCTT
TAGTCAAAATCTTGCGTTAATGCTTAATGCACATATTCATTTAGATGCAACGTTAAAAGCATTTTTATCAGAACATCGCC
AAGATCCGGTATTACATCAGGAGATTTTGAGTATATTAAGTTTATTAAAGCAAGGTTATAAATTCTCTGAGGGGCTTAAT
CCAACCGTATTTACTAGCCAAGTAGTACAAATGATGGCAATTGGCGAACAAAGTGGTAATTTGGCTAAAATGTGTATGTG
TATTAGTCAACTGTATCAGCAAAAACTAGACTACCAAATTGATTTGTTTGCTCAATTACTTGAACCGGTTTTAATGTTAG
TGATTGGCATTATTGTGGGGACGATTTTGATTGGGATTTATTTGCCTATTTTTGATATGGGAGCATTGGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

51.134

100

0.511
  pilC Haemophilus influenzae Rd KW20

39.75

100

0.401
  pilC Haemophilus influenzae 86-028NP

39.25

100

0.395

Multiple sequence alignment