Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL147_RS08380 Genome accession   NZ_LR134341
Coordinates   1706221..1706907 (+) Length   228 a.a.
NCBI ID   WP_003082738.1    Uniprot ID   A0A4V0H8F5
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1701221..1711907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS08355 (NCTC13786_01676) ktrB 1701466..1702842 (-) 1377 WP_007894878.1 potassium uptake transporter channel subunit KtrB -
  EL147_RS08360 (NCTC13786_01677) rsmG 1702927..1703640 (-) 714 WP_007894900.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL147_RS08365 (NCTC13786_01678) - 1703789..1704343 (+) 555 WP_007894897.1 LemA family protein -
  EL147_RS08370 (NCTC13786_01679) htpX 1704377..1705273 (+) 897 WP_007894957.1 zinc metalloprotease HtpX -
  EL147_RS08375 (NCTC13786_01680) - 1705469..1706002 (+) 534 WP_007894876.1 DUF177 domain-containing protein -
  EL147_RS08380 (NCTC13786_01681) covR 1706221..1706907 (+) 687 WP_003082738.1 two-component system response regulator CovR Regulator
  EL147_RS08385 (NCTC13786_01682) - 1706917..1708398 (+) 1482 WP_007894935.1 HAMP domain-containing histidine kinase -
  EL147_RS08390 (NCTC13786_01683) nrdR 1708594..1709088 (+) 495 WP_007894853.1 transcriptional regulator NrdR -
  EL147_RS08395 (NCTC13786_01684) - 1709075..1710262 (+) 1188 WP_007896447.1 DnaD domain protein -
  EL147_RS08400 (NCTC13786_01685) dnaI 1710263..1711165 (+) 903 WP_007894955.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26623.61 Da        Isoelectric Point: 4.6541

>NTDB_id=1122028 EL147_RS08380 WP_003082738.1 1706221..1706907(+) (covR) [Streptococcus pseudoporcinus strain NCTC13786]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1122028 EL147_RS08380 WP_003082738.1 1706221..1706907(+) (covR) [Streptococcus pseudoporcinus strain NCTC13786]
ATGACAAAGAAAATTCTAATTGTCGAAGATGAAAAAAATCTCGCACGGTTTGTTTCACTTGAACTTCAACATGAAGGGTA
CGAGGTGACAGTAGAAGTAAACGGGCGTGAAGGCCTAGAAACAGCATTAGAAAAAGATTTTGATTTAATTTTACTAGATT
TAATGCTCCCTGAAATGGACGGTTTTGAAGTCACTCGTCGTCTTCAAACTGAGAAAACTACCTATATCATGATGATGACT
GCACGTGATTCTATTATGGACGTTGTAGCAGGTCTTGATCGTGGTGCAGATGATTATATTGTCAAACCATTTGCTATTGA
AGAGTTATTAGCGCGTATTCGGGCGATTTTCCGTCGTCAAGACATTGAAACTGAAAAGAAAGCGCCTAATCAAGGTGTTT
ATCGCGACCTTGTTTTGAACCCTCAAAACAGATCTGTGAACCGTGGTGATGATGAAATTTCATTAACAAAGCGTGAGTAT
GATCTCTTGAATATCCTTATGACAAATATGAATCGTGTAATGACCCGCGAAGAGTTGCTTTCTAATGTTTGGAAATACGA
TGAAGCCGTTGAAACAAATGTTGTTGATGTCTACATTCGTTATCTTCGTGGCAAAATTGACATGCCTGGTCGTGAATCCT
ATATTCAGACTGTTCGTGGCATGGGTTATGTTATCCGTGAAAAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H8F5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.969

100

0.833
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434

Multiple sequence alignment