Detailed information NTG1121538

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: EL133_RS07275
• Genome accession: NZ_LR134323
• Coordinates: 1423182..1423889 (-)
• Length: 235 a.a.
• NCBI ID: WP_006738790.1
• Uniprot ID: G5KHX0
• Organism: Streptococcus urinalis strain NCTC13766
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1418182..1428889

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL133_RS07250 (NCTC13766_01512)	pstB	1418365..1419117 (-)	753	WP_006738485.1	phosphate ABC transporter ATP-binding protein PstB	-
EL133_RS07255 (NCTC13766_01513)	pstA	1419121..1419936 (-)	816	WP_006740147.1	phosphate ABC transporter permease PstA	-
EL133_RS07260 (NCTC13766_01514)	pstC	1419929..1420792 (-)	864	WP_006738400.1	phosphate ABC transporter permease subunit PstC	-
EL133_RS07265 (NCTC13766_01515)	-	1420854..1421735 (-)	882	WP_006739838.1	substrate-binding domain-containing protein	-
EL133_RS07270 (NCTC13766_01516)	pnpS	1421841..1423178 (-)	1338	WP_006738474.1	two-component system histidine kinase PnpS	-
EL133_RS07275 (NCTC13766_01517)	vicR	1423182..1423889 (-)	708	WP_006738790.1	response regulator transcription factor	Regulator
EL133_RS07280 (NCTC13766_01518)	-	1423973..1425013 (-)	1041	WP_006739192.1	LLM class flavin-dependent oxidoreductase	-
EL133_RS07285 (NCTC13766_01519)	-	1425082..1425462 (-)	381	WP_006738448.1	VOC family protein	-
EL133_RS07290 (NCTC13766_01520)	-	1425652..1425798 (+)	147	WP_006740355.1	SPJ_0845 family protein	-
EL133_RS07295 (NCTC13766_01521)	-	1425884..1426789 (+)	906	WP_006739782.1	permease	-
EL133_RS07300 (NCTC13766_01522)	-	1426786..1427601 (+)	816	WP_006740614.1	TIGR03943 family putative permease subunit	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27440.81 Da
• Isoelectric Point: 4.9878

>NTDB_id=1121538 EL133_RS07275 WP_006738790.1 1423182..1423889(-) (vicR) [Streptococcus urinalis strain NCTC13766]
MKKQILIVDDELPILTLLDYHLVKEGYQVKTAEDGRTALNLALTEHFDLIVLDIMLPQLDGIEVCKRLRAQHKKTPIIML
SAKGDEFDKVFALELGADDYMTKPFSPRELMARIKAVLRRTDNDQLEEDEDMISDDVLEIDYLKIYPDRHEIYCQDQLVS
LTPKEFELLLYLAKHPKMTLTRERLLERIWGYDFGLETRLVDVHIGKLREKIEQDPKSPQFIKTVRGYGYKFEGA

Nucleotide

• Length: 708 bp

>NTDB_id=1121538 EL133_RS07275 WP_006738790.1 1423182..1423889(-) (vicR) [Streptococcus urinalis strain NCTC13766]
ATGAAAAAACAGATACTTATTGTAGATGATGAATTGCCTATTTTGACATTATTAGATTATCATTTAGTTAAAGAAGGCTA
TCAAGTTAAAACAGCTGAAGATGGTAGAACAGCACTGAATTTAGCATTAACTGAACATTTTGATTTAATAGTATTGGATA
TTATGTTGCCTCAGTTGGATGGTATTGAAGTTTGTAAAAGATTGAGAGCTCAACATAAAAAGACACCAATTATTATGCTC
TCTGCTAAAGGTGATGAGTTTGATAAAGTTTTTGCTTTAGAACTAGGTGCGGATGACTACATGACAAAACCATTTAGCCC
AAGAGAATTAATGGCTAGGATTAAAGCAGTTTTAAGACGAACTGACAATGATCAATTAGAAGAAGACGAAGATATGATTT
CAGATGATGTATTAGAAATTGACTATCTTAAAATCTATCCAGATCGTCACGAAATTTATTGTCAAGATCAGCTTGTTTCA
CTAACACCAAAAGAATTTGAATTATTACTTTACTTAGCAAAACATCCCAAAATGACATTAACTAGAGAAAGACTCTTAGA
GAGAATATGGGGTTATGACTTTGGACTTGAAACCAGACTAGTGGATGTCCATATTGGAAAACTGAGAGAAAAGATTGAGC
AAGATCCAAAATCACCACAATTTATAAAAACAGTGAGAGGTTATGGTTACAAATTTGAAGGAGCCTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-115)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (157-232)

3D structure

• AlphaFold DB: G5KHX0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	52.814	98.298	0.519
micA	Streptococcus pneumoniae Cp1015	50	97.021	0.485
covR	Streptococcus salivarius strain HSISS4	43.043	97.872	0.421
covR	Lactococcus lactis subsp. lactis strain DGCC12653	40.611	97.447	0.396