Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL133_RS01225 Genome accession   NZ_LR134323
Coordinates   238937..239623 (+) Length   228 a.a.
NCBI ID   WP_006739393.1    Uniprot ID   G5KHR6
Organism   Streptococcus urinalis strain NCTC13766     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 233937..244623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS01200 (NCTC13766_00239) ktrB 234257..235633 (-) 1377 WP_006740251.1 potassium uptake transporter channel subunit KtrB -
  EL133_RS01205 (NCTC13766_00240) rsmG 235716..236429 (-) 714 WP_006738738.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL133_RS01210 (NCTC13766_00241) - 236594..237151 (+) 558 WP_006739376.1 LemA family protein -
  EL133_RS01215 (NCTC13766_00242) htpX 237169..238065 (+) 897 WP_006739951.1 zinc metalloprotease HtpX -
  EL133_RS01220 (NCTC13766_00243) - 238188..238724 (+) 537 WP_006738861.1 DUF177 domain-containing protein -
  EL133_RS01225 (NCTC13766_00244) covR 238937..239623 (+) 687 WP_006739393.1 response regulator transcription factor Regulator
  EL133_RS01230 (NCTC13766_00245) - 239626..241161 (+) 1536 WP_006739083.1 HAMP domain-containing histidine kinase -
  EL133_RS01235 (NCTC13766_00246) nrdR 241283..241774 (+) 492 WP_006739490.1 transcriptional regulator NrdR -
  EL133_RS01240 (NCTC13766_00247) - 241761..242930 (+) 1170 WP_126430485.1 DnaD domain protein -
  EL133_RS01245 (NCTC13766_00248) dnaI 242931..243827 (+) 897 WP_006739378.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26626.70 Da        Isoelectric Point: 4.7053

>NTDB_id=1121509 EL133_RS01225 WP_006739393.1 238937..239623(+) (covR) [Streptococcus urinalis strain NCTC13766]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEYNGREGLESALEKDFDLILLDLMLPEMDGFEITRRLQQEKDTYIMMMT
ARDSVMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIDLNKKAVNQGVYRDLSLNPQNRSVLRGDVEISLTKREF
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1121509 EL133_RS01225 WP_006739393.1 238937..239623(+) (covR) [Streptococcus urinalis strain NCTC13766]
ATGACTAAAAAAATACTAATTGTCGAAGATGAGAAAAATCTTGCTCGCTTTGTCTCATTAGAGTTACAGCACGAAGGCTA
TGAAGTTACAGTAGAATACAACGGTCGTGAAGGACTTGAGTCTGCTTTAGAAAAAGATTTTGATTTAATTCTTTTAGACT
TAATGCTTCCAGAAATGGATGGATTTGAAATCACTCGACGTCTTCAACAAGAAAAAGACACATATATCATGATGATGACA
GCACGTGATTCTGTGATGGATGTTGTTGCAGGTCTTGATCGTGGTGCTGATGATTATATTGTAAAACCTTTTGCCATTGA
AGAATTATTAGCTCGCATCCGTGCTATTTTCAGACGTCAAGATATTGATTTAAACAAAAAAGCTGTAAATCAAGGTGTTT
ACCGTGACTTAAGTTTAAATCCACAAAATCGTTCTGTTTTACGTGGAGATGTTGAAATTTCACTGACAAAACGTGAGTTT
GATTTACTTAATATCTTAATGACCAACATGAATCGTGTTATGACACGTGAAGAACTATTATCTAATGTTTGGAAATACGA
TGAAGCAGTTGAAACCAATGTTGTTGATGTGTACATCCGTTATTTACGTGGAAAAATTGACATGCCTGGTAAAGAATCTT
ATATTCAAACTGTTCGTGGCATGGGGTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5KHR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.969

100

0.833
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.079

99.561

0.658
  micA Streptococcus pneumoniae Cp1015

42.489

100

0.434
  vicR Streptococcus mutans UA159

42.424

100

0.43

Multiple sequence alignment