Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   EL130_RS00605 Genome accession   NZ_LR134320
Coordinates   110597..111922 (-) Length   441 a.a.
NCBI ID   WP_002277687.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 105597..116922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS10370 - 105653..105784 (+) 132 WP_002285725.1 hypothetical protein -
  EL130_RS00560 (NCTC10832_00104) - 105978..106142 (-) 165 WP_002265308.1 hypothetical protein -
  EL130_RS10270 - 106582..106794 (+) 213 Protein_103 IS3 family transposase -
  EL130_RS00575 (NCTC10832_00105) - 106917..107321 (-) 405 WP_002263912.1 hypothetical protein -
  EL130_RS00580 (NCTC10832_00106) - 107468..107887 (-) 420 WP_002263913.1 hypothetical protein -
  EL130_RS00590 (NCTC10832_00107) - 109267..109668 (-) 402 WP_002310604.1 hypothetical protein -
  EL130_RS00595 (NCTC10832_00108) cipB 109799..110029 (-) 231 WP_002283381.1 Blp family class II bacteriocin Regulator
  EL130_RS00600 (NCTC10832_00109) comC/blpC 110297..110428 (+) 132 WP_002273928.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  EL130_RS00605 (NCTC10832_00110) comD/blpH 110597..111922 (-) 1326 WP_002277687.1 sensor histidine kinase Regulator
  EL130_RS00610 (NCTC10832_00111) comE/blpR 111919..112671 (-) 753 WP_002277686.1 response regulator transcription factor Regulator
  EL130_RS00615 (NCTC10832_00112) - 113136..113774 (-) 639 WP_002262115.1 VTT domain-containing protein -
  EL130_RS00620 (NCTC10832_00113) - 113822..114448 (-) 627 WP_002277685.1 hypothetical protein -
  EL130_RS00625 (NCTC10832_00114) der 114523..115833 (-) 1311 WP_002277684.1 ribosome biogenesis GTPase Der -
  EL130_RS00630 (NCTC10832_00115) dnaI 115846..116745 (-) 900 WP_002265120.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50503.76 Da        Isoelectric Point: 9.8662

>NTDB_id=1121385 EL130_RS00605 WP_002277687.1 110597..111922(-) (comD/blpH) [Streptococcus mutans strain NCTC10832]
MNEALMILLNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMDSSIVTTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYIIESYNVIPVLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIQSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPDMELLDFITILSILCDNAIEAALESLKPKVQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1121385 EL130_RS00605 WP_002277687.1 110597..111922(-) (comD/blpH) [Streptococcus mutans strain NCTC10832]
ATGAATGAAGCCTTAATGATACTTTTAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCCAA
GGTAAGTAATGTTACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGACAGTAGCATTGTAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATATTATAGAGAGTTATAATGTGATACC
GGTTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATTACCCAGTATAGTCAGCAGATA
GAATCTCTTTACAAGGATATTCAAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGTCATCTAGCTAATATCCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATTTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGATATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCTATTGAGGCCGCTCTCGAATCACTAAAACCTAAAGTTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACTAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

96.825

100

0.968

Multiple sequence alignment