Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL136_RS00145 Genome accession   NZ_LR134317
Coordinates   25231..25917 (+) Length   228 a.a.
NCBI ID   WP_012516253.1    Uniprot ID   U5Y8A0
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 20231..30917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS00125 (NCTC6180_00026) rsmG 21893..22606 (-) 714 WP_012516257.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL136_RS00130 (NCTC6180_00027) - 22742..23299 (+) 558 WP_154803554.1 LemA family protein -
  EL136_RS00135 (NCTC6180_00028) htpX 23331..24224 (+) 894 WP_111678521.1 zinc metalloprotease HtpX -
  EL136_RS00140 (NCTC6180_00029) - 24513..25046 (+) 534 WP_154803555.1 YceD family protein -
  EL136_RS00145 (NCTC6180_00030) covR 25231..25917 (+) 687 WP_012516253.1 two-component system response regulator CovR Regulator
  EL136_RS00150 (NCTC6180_00031) - 25921..27411 (+) 1491 WP_154803556.1 HAMP domain-containing histidine kinase -
  EL136_RS00155 (NCTC6180_00032) nrdR 27602..28096 (+) 495 WP_012516251.1 transcriptional regulator NrdR -
  EL136_RS00160 (NCTC6180_00033) - 28080..29243 (+) 1164 WP_172453605.1 helicase loader -
  EL136_RS00165 (NCTC6180_00034) dnaI 29244..30152 (+) 909 WP_154803557.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26580.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1121252 EL136_RS00145 WP_012516253.1 25231..25917(+) (covR) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1121252 EL136_RS00145 WP_012516253.1 25231..25917(+) (covR) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAGAATCTTGCAAGATTTGTTTCGCTTGAGCTACAACATGAGGGTTA
CGAGGTGACCGTCGAGGTTAATGGTCGTGAGGGCTTGGAGACAGCCCTAGAGAAGGACTTTGACTTAATCCTTCTTGATT
TGATGCTTCCTGAGATGGACGGATTTGAAGTGACACGTCGATTGCAAACAGAAAAAACGACTTACATCATGATGATGACT
GCGCGTGACTCTATTATGGACGTTGTAGCCGGCTTGGATCGTGGTGCTGATGATTATATCGTGAAGCCATTTGCCATTGA
GGAATTGCTGGCGCGTATTCGTGCTATCTTCCGTCGTCAGGACATTGAGTCAGAGAAAAAGACTCCTAGTCAAGGCGTTT
ACCGCGACTTAGTCTTAAACCCTCAAAACCGCTCTGTCAATCGCGGTGATGACGAGATTTCACTGACTAAGCGTGAATAT
GACCTGCTTAATATTTTGATGACAAACATGAATCGTGTCATGACTCGTGAGGAGCTCTTATCTAACGTTTGGAAATATGA
TGAGGCTGTTGAAACTAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGGAAGATCGATATCCCTGGGAAAGAGTCTT
ACATTCAAACTGTTCGTGGAATGGGTTATGTGATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U5Y8A0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.533

100

0.829
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment