Detailed information NTG1121213

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EL139_RS03075
• Genome accession: NZ_LR134316
• Coordinates: 563862..564773 (-)
• Length: 303 a.a.
• NCBI ID: WP_111714689.1
• Uniprot ID: A0A9X8SXJ1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 558862..569773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL139_RS03055 (NCTC6181_00623)	-	559877..561652 (-)	1776	WP_111714700.1	acyltransferase family protein	-
EL139_RS03060 (NCTC6181_00624)	-	561649..562050 (-)	402	WP_111714697.1	MORN repeat-containing protein	-
EL139_RS03065 (NCTC6181_00625)	-	562079..562510 (-)	432	WP_111714695.1	low molecular weight protein-tyrosine-phosphatase	-
EL139_RS03070 (NCTC6181_00626)	ruvB	562645..563643 (-)	999	WP_111714692.1	Holliday junction branch migration DNA helicase RuvB	-
EL139_RS11285 (NCTC6181_00627)	comS	563677..563775 (-)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
EL139_RS03075 (NCTC6181_00628)	comR	563862..564773 (-)	912	WP_111714689.1	XRE family transcriptional regulator	Regulator
EL139_RS03080 (NCTC6181_00629)	purB	564916..566208 (-)	1293	WP_111714687.1	adenylosuccinate lyase	-
EL139_RS03085 (NCTC6181_00630)	purK	566218..567312 (-)	1095	WP_111714684.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EL139_RS03090 (NCTC6181_00631)	purE	567299..567787 (-)	489	WP_102776662.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
EL139_RS03095 (NCTC6181_00632)	purD	568188..569450 (-)	1263	WP_111714682.1	phosphoribosylamine--glycine ligase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35895.50 Da
• Isoelectric Point: 4.7310

>NTDB_id=1121213 EL139_RS03075 WP_111714689.1 563862..564773(-) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFNEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=1121213 EL139_RS03075 WP_111714689.1 563862..564773(-) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGCTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGCAAATTACAGGTCCGAGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTAATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAGTACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTATCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	45.819	98.68	0.452
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449