Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL139_RS01155 Genome accession   NZ_LR134316
Coordinates   200257..200943 (-) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 195257..205943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS01135 (NCTC6181_00234) - 195565..196743 (-) 1179 WP_111715260.1 DnaD domain protein -
  EL139_RS01140 (NCTC6181_00235) nrdR 196727..197221 (-) 495 WP_003049740.1 transcriptional regulator NrdR -
  EL139_RS01145 (NCTC6181_00236) - 197395..198528 (-) 1134 WP_111714946.1 ISAs1 family transposase -
  EL139_RS01150 (NCTC6181_00237) - 198752..200251 (-) 1500 WP_111715255.1 HAMP domain-containing histidine kinase -
  EL139_RS01155 (NCTC6181_00238) covR 200257..200943 (-) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  EL139_RS01160 (NCTC6181_00239) - 201213..201746 (-) 534 WP_111715253.1 DUF177 domain-containing protein -
  EL139_RS01165 (NCTC6181_00240) htpX 202012..202905 (-) 894 WP_111715251.1 zinc metalloprotease HtpX -
  EL139_RS01170 (NCTC6181_00241) - 202950..203507 (-) 558 WP_111715248.1 LemA family protein -
  EL139_RS01175 (NCTC6181_00242) rsmG 203660..204373 (+) 714 WP_111715245.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL139_RS01180 (NCTC6181_00243) ktrB 204457..205833 (+) 1377 WP_111715242.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1121195 EL139_RS01155 WP_003049736.1 200257..200943(-) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1121195 EL139_RS01155 WP_003049736.1 200257..200943(-) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
TGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGAATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment