Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL097_RS00840 Genome accession   NZ_LR134293
Coordinates   168034..168720 (-) Length   228 a.a.
NCBI ID   WP_003046762.1    Uniprot ID   -
Organism   Streptococcus canis strain NCTC12191     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 163034..173720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS00820 (NCTC12191_00160) dnaI 163757..164659 (-) 903 WP_003046771.1 primosomal protein DnaI -
  EL097_RS00825 (NCTC12191_00161) - 164660..165829 (-) 1170 WP_003046769.1 DnaD domain protein -
  EL097_RS00830 (NCTC12191_00162) nrdR 165813..166307 (-) 495 WP_003046767.1 transcriptional regulator NrdR -
  EL097_RS00835 (NCTC12191_00163) - 166526..168028 (-) 1503 WP_003046765.1 HAMP domain-containing histidine kinase -
  EL097_RS00840 (NCTC12191_00164) covR 168034..168720 (-) 687 WP_003046762.1 two-component system response regulator CovR Regulator
  EL097_RS00845 (NCTC12191_00165) - 168981..169514 (-) 534 WP_003046759.1 DUF177 domain-containing protein -
  EL097_RS00850 (NCTC12191_00166) htpX 169789..170691 (-) 903 WP_099982901.1 zinc metalloprotease HtpX -
  EL097_RS00855 (NCTC12191_00167) - 170739..171296 (-) 558 WP_003046754.1 LemA family protein -
  EL097_RS00860 (NCTC12191_00168) rsmG 171446..172159 (+) 714 WP_003046751.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL097_RS00865 (NCTC12191_00169) ktrB 172240..173616 (+) 1377 WP_003046748.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26575.63 Da        Isoelectric Point: 4.6541

>NTDB_id=1120476 EL097_RS00840 WP_003046762.1 168034..168720(-) (covR) [Streptococcus canis strain NCTC12191]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKLPSQGIYRDLVLNPQNRSVNRGDDEIPLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1120476 EL097_RS00840 WP_003046762.1 168034..168720(-) (covR) [Streptococcus canis strain NCTC12191]
ATGACAAAGAAAATTTTAATTATCGAAGATGAAAAAAATCTCGCAAGGTTTGTTTCACTTGAACTGCAACATGAAGGTTA
TGAAGTAACCGTTGAAGTAAATGGTCGTGAAGGGTTAGAAACTGCCTTGGAAAAGGATTTTGATTTAATCTTGCTTGACT
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACCCGTCGCTTACAGACTGAAAAAACAACATATATCATGATGATGACT
GCACGTGATTCGATTATGGATGTGGTGGCAGGCTTGGACCGTGGTGCGGATGACTATATTGTTAAGCCATTTGCGATTGA
AGAATTGTTGGCTCGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAATCTGAAAAGAAACTGCCTAGTCAAGGAATTT
ATCGTGACTTGGTCTTGAACCCGCAAAACCGTTCGGTTAATCGTGGGGATGATGAAATTCCCCTCACTAAACGTGAATAC
GACTTGCTTAGCATTTTGATGACAAACATGAACCGTGTGATGACACGTGAAGAATTGCTCTCAAATGTTTGGAAATATGA
TGAGGCAGTTGAAACAAACGTTGTTGATGTTTATATTCGTTACCTTCGTGGTAAAGTTGACATCCCAGGTAAGGAATCTT
ATATCCAAACCGTTCGCGGCATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.103

100

0.439
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.421

Multiple sequence alignment