Detailed information NTG1120432

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL084_RS02185
• Genome accession: NZ_LR134292
• Coordinates: 425438..427696 (+)
• Length: 752 a.a.
• NCBI ID: WP_126440038.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC10389
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 420438..432696

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL084_RS02155 (NCTC10389_00455)	-	421014..421880 (+)	867	WP_126440034.1	AraC family transcriptional regulator	-
EL084_RS02160 (NCTC10389_00456)	-	421890..422780 (+)	891	WP_126440035.1	ROK family protein	-
EL084_RS02165 (NCTC10389_00457)	-	422794..423069 (-)	276	WP_004230871.1	GIY-YIG nuclease family protein	-
EL084_RS02170 (NCTC10389_00458)	-	423044..423805 (-)	762	WP_004230873.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EL084_RS02175 (NCTC10389_00459)	-	423924..424670 (+)	747	WP_126440036.1	lysophospholipid acyltransferase family protein	-
EL084_RS02180 (NCTC10389_00460)	-	424765..425445 (+)	681	WP_126440037.1	helix-hairpin-helix domain-containing protein	-
EL084_RS02185 (NCTC10389_00461)	comEC/celB	425438..427696 (+)	2259	WP_126440038.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL084_RS02190 (NCTC10389_00462)	holA	427735..428772 (+)	1038	WP_044023236.1	DNA polymerase III subunit delta	-
EL084_RS02195 (NCTC10389_00463)	sodA	428869..429480 (+)	612	WP_044023237.1	superoxide dismutase SodA	-
EL084_RS02200 (NCTC10389_00464)	-	429586..430308 (+)	723	Protein_402	YebC/PmpR family DNA-binding transcriptional regulator	-
EL084_RS02205 (NCTC10389_00465)	queA	430355..431383 (-)	1029	WP_126440039.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
EL084_RS02210 (NCTC10389_00466)	-	431543..432049 (+)	507	WP_004230888.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 85094.89 Da
• Isoelectric Point: 9.5372

>NTDB_id=1120432 EL084_RS02185 WP_126440038.1 425438..427696(+) (comEC/celB) [Streptococcus equinus strain NCTC10389]
MIKHFPIKPIQLAFLHILVYYFCFLKFFWCLVLLLLALICLWKNYGSKKLWQTLIILMCFASFISFKNQQAEQADKVAPA
HLSKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYTLKSEKEQQFFKSLNQTLVLSGEINLEKATPQRNFGGFDYRTYLKH
EGIYRIGNLSSIVGMRRQTSLNLVERLHDLRRKAIVSIQQNFPAPMQHYMTGLLFGYLDKSFDEMIDIYTSLGIIHLFAL
SGMQVGFFVGIFRYFFLRLGLRRDYVDILQIPFSIVYAGLTGFSVSVVRSLIQSGLGNIGVKRLDNLALTMMILFCIMSN
FLLTTGGILSFTYAFILSFIDFVELESYQKKIVECLAISLGSLPILIYFFSVFQPMSILLTAIFSLAFDTLMLPVLSVVF
LISPLVRLSIFNSFFIVLEDVIKLTMNFLGGPIVFGKPSIGILVFLLFSLGVLYDYRQKRKVVIFLISLVALLFFHIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSPKEGWQERLSDSNADRTLIPYLNSRGIGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEVLVSQGSLTKPDFVAKLQAMKTKVRTVSAGDSLPIMGSSLQVLYPIRVGDGSNNDSVVLYGKLLGK
NFLFTGDLEEEGEREVMVTYPNLPVDVLKAGHHGSKGSSSPAFLAHISPQIALISAGQNNRYKHPHQETLERFQAQNMTT
YRTDQQGAIRFRGLNHWKIETMRRAFFTNFLW

Nucleotide

• Length: 2259 bp

>NTDB_id=1120432 EL084_RS02185 WP_126440038.1 425438..427696(+) (comEC/celB) [Streptococcus equinus strain NCTC10389]
TTGATTAAACATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCACATTCTCGTTTATTACTTTTGCTTTTTGAAGTT
CTTTTGGTGTTTAGTCCTCCTTTTATTAGCCCTGATCTGCTTATGGAAAAACTACGGTTCTAAAAAATTGTGGCAAACCT
TGATAATTCTGATGTGCTTTGCTAGTTTTATTAGTTTTAAAAATCAGCAAGCAGAGCAAGCTGACAAAGTAGCGCCAGCT
CATTTATCAAAAATCCAGATGATTCCAGACACGATTTCGGTCAATGGTGACTTGCTGTCTTTTCGAGGAAAGGAGGCTGG
ACAGACTTATCAAGTCTTTTATACTTTGAAGTCAGAAAAGGAGCAGCAATTTTTTAAAAGTCTTAATCAAACGCTTGTCT
TGTCTGGTGAGATTAACTTGGAGAAAGCAACGCCTCAGCGTAATTTTGGTGGGTTTGACTATCGGACTTACTTGAAACAT
GAAGGTATTTATCGCATTGGGAATCTTTCTTCAATTGTTGGGATGAGACGTCAAACTTCTTTGAATTTGGTTGAGCGACT
GCATGATTTGCGACGAAAAGCAATTGTTAGCATCCAGCAAAATTTTCCAGCACCCATGCAACATTATATGACGGGGCTTT
TGTTTGGTTATCTGGATAAATCTTTTGATGAGATGATCGATATTTACACGAGTTTAGGAATTATTCATCTCTTTGCTCTT
TCCGGTATGCAGGTTGGCTTTTTTGTCGGTATTTTTCGCTATTTCTTTTTGCGACTAGGCTTAAGACGTGATTATGTTGA
CATTCTTCAAATCCCTTTTTCGATTGTATATGCTGGTTTGACAGGATTTTCAGTGTCAGTTGTCCGAAGTCTCATTCAGT
CAGGTTTAGGCAATATTGGCGTTAAGCGACTTGATAATCTTGCTTTGACTATGATGATTCTTTTCTGCATTATGTCTAAT
TTCCTGCTGACAACGGGAGGCATTTTGTCATTTACTTATGCCTTTATTCTAAGTTTTATTGATTTTGTGGAACTTGAAAG
TTATCAGAAGAAAATTGTAGAATGCTTGGCAATTTCATTAGGTAGCTTACCAATTTTGATTTACTTTTTTTCAGTTTTTC
AACCGATGTCCATTCTTTTGACAGCTATTTTTTCATTGGCATTTGATACGCTTATGTTGCCAGTTCTGTCAGTGGTTTTC
TTGATTTCGCCACTCGTGAGATTATCAATTTTTAATAGCTTTTTTATCGTTTTAGAAGATGTGATAAAGCTGACTATGAA
TTTCCTTGGTGGTCCGATTGTTTTTGGCAAACCAAGTATTGGTATTTTGGTTTTTTTATTATTTAGCTTGGGTGTTCTTT
ATGATTACAGGCAGAAAAGGAAAGTTGTAATTTTTCTTATCAGCTTAGTAGCTCTGCTATTTTTCCACATCAAGCATCCG
CTGGAAAACGAAGTGACGGTGGTTGACATCGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAAGGGCATACGCTGTT
AATTGATGTCGGAGGAAAAGTGAGTTTTAGCCCAAAAGAAGGCTGGCAGGAGCGTTTGTCTGACAGCAACGCAGATCGAA
CCTTGATTCCGTATCTCAATAGCCGTGGCATTGGAAAAATTGACCAGCTGGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGTTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAGTTTTGGTTAGTCAAGGAAGTTTGACAAAGCCAGATTT
TGTGGCAAAATTACAAGCTATGAAAACCAAGGTTCGCACAGTTTCTGCTGGAGATAGTCTACCGATTATGGGAAGTAGCT
TGCAGGTGCTGTACCCTATTAGAGTTGGCGATGGTTCTAATAATGATTCGGTGGTGTTGTATGGCAAGCTTCTTGGTAAA
AATTTTCTGTTTACAGGAGATTTGGAAGAAGAAGGTGAGCGCGAGGTGATGGTGACTTATCCTAATTTGCCAGTTGATGT
TTTAAAAGCAGGACACCATGGCTCAAAAGGGTCATCAAGCCCAGCATTTCTAGCCCATATTTCACCGCAGATTGCTCTGA
TTTCTGCAGGTCAAAATAACCGTTATAAGCACCCTCACCAAGAAACGCTTGAACGATTTCAAGCGCAAAATATGACCACT
TACCGCACAGACCAACAAGGCGCCATCCGCTTTAGAGGATTAAACCACTGGAAAATTGAAACGATGAGGCGAGCTTTTTT
TACAAACTTTCTTTGGTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-696)

• Competence protein (Competence) (213-459)

• Domain of unknown function (DUF4131) (DUF4131) (30-172)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	51.752	98.67	0.511
comEC/celB	Streptococcus mitis NCTC 12261	51.348	98.67	0.507
comEC/celB	Streptococcus pneumoniae TIGR4	50.606	98.803	0.5
comEC/celB	Streptococcus pneumoniae Rx1	50.067	98.803	0.495
comEC/celB	Streptococcus pneumoniae D39	50.067	98.803	0.495
comEC/celB	Streptococcus pneumoniae R6	50.067	98.803	0.495
comEC	Lactococcus lactis subsp. cremoris KW2	47.114	99.069	0.467