Detailed information NTG1120249

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EL087_RS02005
• Genome accession: NZ_LR134288
• Coordinates: 395998..396657 (-)
• Length: 219 a.a.
• NCBI ID: WP_126406547.1
• Uniprot ID: A0A4U9YE04
• Organism: Streptococcus milleri strain NCTC11169
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 390998..401657

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL087_RS01975 (NCTC11169_00396)	sepM	391455..392510 (+)	1056	WP_126406544.1	SepM family pheromone-processing serine protease	Regulator
EL087_RS01980 (NCTC11169_00397)	-	392650..393213 (+)	564	WP_003043206.1	YutD family protein	-
EL087_RS01985 (NCTC11169_00398)	rlmN	393247..394329 (+)	1083	WP_022525296.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EL087_RS01990 (NCTC11169_00399)	-	394322..394852 (+)	531	WP_003028375.1	VanZ family protein	-
EL087_RS01995	-	395241..395678 (-)	438	Protein_349	ISL3 family transposase	-
EL087_RS02000	-	395675..395836 (+)	162	Protein_350	tryptophan synthase subunit beta	-
EL087_RS02005 (NCTC11169_00401)	cclA/cilC	395998..396657 (-)	660	WP_126406547.1	prepilin peptidase	Machinery gene
EL087_RS02010 (NCTC11169_00402)	-	396811..397338 (+)	528	WP_126406550.1	Dps family protein	-
EL087_RS02015 (NCTC11169_00403)	-	397612..397836 (+)	225	WP_003025724.1	YqgQ family protein	-
EL087_RS02020 (NCTC11169_00404)	-	397830..398210 (+)	381	WP_106082915.1	rhodanese-like domain-containing protein	-
EL087_RS02025 (NCTC11169_00405)	-	398230..398955 (-)	726	WP_106100128.1	16S rRNA pseudouridine(516) synthase	-
EL087_RS02030 (NCTC11169_00406)	typA	399133..400974 (+)	1842	WP_057489582.1	translational GTPase TypA	-
EL087_RS02035 (NCTC11169_00407)	-	401039..401323 (+)	285	WP_003043425.1	DUF3165 family protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24806.17 Da
• Isoelectric Point: 8.2271

>NTDB_id=1120249 EL087_RS02005 WP_126406547.1 395998..396657(-) (cclA/cilC) [Streptococcus milleri strain NCTC11169]
MIHFYFFLVGSIVASFLGLVVDRFPEQSILVPSSHCNACGQKLAPRDLVPVLSQLINRLRCRFCQSKIPIRYLVLEIAIG
SLFLATSMGYLNIGQLVLLVMGITLSLYDQREQEYPLLIWLFFHFLLLFLTGFNLLMISFLTLGIVAFFFDLRIGAGDFL
FLASCSTVFKLTEILWLIQIASLVGLCLFCLKKRKDRIAFVPCLLIGVIVLLLCELLLQ

Nucleotide

• Length: 660 bp

>NTDB_id=1120249 EL087_RS02005 WP_126406547.1 395998..396657(-) (cclA/cilC) [Streptococcus milleri strain NCTC11169]
ATGATTCATTTTTATTTTTTCTTGGTTGGAAGCATTGTGGCTTCCTTTTTAGGGCTGGTCGTTGATCGTTTCCCTGAACA
GTCTATTCTCGTTCCTTCCAGTCATTGTAATGCTTGTGGACAGAAATTAGCACCTCGCGATTTAGTCCCTGTCCTTTCTC
AGCTTATCAATCGACTGCGTTGTCGGTTTTGTCAGTCAAAAATTCCCATCCGCTATTTGGTATTAGAAATCGCTATCGGA
TCTCTCTTTCTTGCAACTTCTATGGGCTATCTAAATATCGGTCAGCTTGTCCTACTTGTAATGGGCATAACCTTATCCCT
TTACGATCAAAGAGAACAAGAATATCCTCTGCTTATTTGGCTGTTTTTCCATTTCCTTCTTCTCTTTTTAACAGGTTTCA
ATCTTCTAATGATTAGTTTTTTAACCCTTGGAATAGTAGCTTTTTTCTTTGACTTACGAATTGGCGCAGGAGACTTTCTT
TTTCTAGCTTCTTGTTCAACTGTTTTCAAGTTGACAGAGATTCTTTGGCTGATTCAAATTGCCAGCTTAGTGGGCTTATG
TCTCTTTTGCTTAAAAAAGAGAAAAGACAGGATAGCTTTCGTTCCCTGTCTTTTGATTGGAGTGATTGTTCTGCTTTTAT
GCGAACTGTTGCTTCAATAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-87)

3D structure

• AlphaFold DB: A0A4U9YE04

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis NCTC 12261	56.422	99.543	0.562
cclA/cilC	Streptococcus mitis SK321	55.963	99.543	0.557
cclA/cilC	Streptococcus pneumoniae TIGR4	55.505	99.543	0.553
cclA/cilC	Streptococcus pneumoniae Rx1	55.046	99.543	0.548
cclA/cilC	Streptococcus pneumoniae D39	55.046	99.543	0.548
cclA/cilC	Streptococcus pneumoniae R6	55.046	99.543	0.548