Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL100_RS09410 Genome accession   NZ_LR134285
Coordinates   1955868..1957241 (-) Length   457 a.a.
NCBI ID   WP_126404062.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1950868..1962241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS09390 (NCTC3168_01932) - 1951277..1952254 (+) 978 WP_126404066.1 Gfo/Idh/MocA family protein -
  EL100_RS09395 (NCTC3168_01933) - 1952256..1953344 (+) 1089 WP_164555431.1 DEAD/DEAH box helicase -
  EL100_RS09400 (NCTC3168_01934) - 1953653..1955038 (-) 1386 WP_126404064.1 polysaccharide deacetylase family protein -
  EL100_RS09405 (NCTC3168_01935) - 1955234..1955620 (-) 387 WP_126404063.1 VOC family protein -
  EL100_RS09410 (NCTC3168_01936) ciaH 1955868..1957241 (-) 1374 WP_126404062.1 sensor histidine kinase Regulator
  EL100_RS09415 (NCTC3168_01937) ciaR 1957231..1957905 (-) 675 WP_006596563.1 response regulator transcription factor Regulator
  EL100_RS09420 (NCTC3168_01938) - 1958019..1958615 (-) 597 WP_126404061.1 hypothetical protein -
  EL100_RS09425 (NCTC3168_01939) - 1958825..1959367 (+) 543 WP_126404060.1 biotin transporter BioY -
  EL100_RS09430 (NCTC3168_01940) - 1959423..1961966 (-) 2544 WP_126404059.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52477.78 Da        Isoelectric Point: 5.9763

>NTDB_id=1120189 EL100_RS09410 WP_126404062.1 1955868..1957241(-) (ciaH) [Streptococcus australis strain NCTC3168]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKMLSKDRYSIISLANRTGNGMGRDEPDDD
RLEDDEPDPEDGPRPSVTSNSTAILLNDNFENVTTDNGFLDLKTVTFSRGYLNKIKQIQITNHYKQKESYRAYLVDIDPD
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFCEIPPSFFDQTFANYEIIAEENDKIFE
YENQVERSLVSDKVLLKQLMTILYDNALKYTEEEGKIRFVAQFKDRYLYLRVEDNGPGISDEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTITVRDNKPKGAIFEVKLATKSDSKKKSGSKSTKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=1120189 EL100_RS09410 WP_126404062.1 1955868..1957241(-) (ciaH) [Streptococcus australis strain NCTC3168]
ATGCTCAATAAAATTAAAAAAACTGTCAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTCTTTACCTTAAT
TTTCTCAACCATGACCTTGATTATTATTCAAGTGATGCGGTCAAGTCTGTATACAACGGTTGATGAAAATTTAAAGATGC
TGAGTAAAGATCGTTATTCTATTATTAGCTTGGCCAATCGTACAGGAAATGGGATGGGAAGAGACGAACCAGATGATGAC
CGACTAGAAGATGATGAGCCTGATCCTGAGGATGGCCCTAGACCATCGGTCACTTCCAATAGTACTGCCATCCTCTTGAA
TGATAATTTTGAAAATGTAACGACGGATAATGGTTTCCTAGATCTAAAAACAGTAACTTTTAGTCGCGGTTATTTAAACA
AGATCAAACAGATTCAAATTACCAATCATTATAAGCAAAAAGAAAGTTACCGAGCTTATTTGGTAGATATTGACCCCGAT
GATTATATCGATGGGGTGAAATACGCCGTAATCATGACCAATATCAGCCAGTTGGAGCAGACCAGTGAAAAACACGAGAG
CCAAATCGCCTTGGTCATGATTTGCTTCTGGGGCATTTCCCTCTTTGCAAGTATCTTCCTGGCTAAAATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAACCGGCAAAAGGCTTTTGTCGAAAATGCCTCTCATGAATTGCGGACACCTTTAGCCGTTTTG
CAAAATCGTTTGGAGACCCTGTTCCGAAAACCAGAGGCAACGATCATGGAATCCAGTGAGAACATCGCCTCCTCTTTGGA
TGAGGTTCGCAATATGCGCTTACTGACGACCAATCTCTTAAACTTAGCCCGTCGAGATGATGGGATTAAACCGGAGTTTT
GTGAAATCCCTCCCTCTTTTTTCGACCAAACCTTTGCCAATTATGAAATCATTGCCGAGGAAAATGATAAAATCTTCGAG
TATGAGAATCAGGTCGAAAGAAGTCTGGTGTCTGACAAGGTCCTACTGAAGCAGCTGATGACCATTTTGTATGACAATGC
CCTCAAATACACAGAGGAAGAAGGAAAGATACGGTTTGTCGCCCAATTCAAGGATCGCTATCTCTATCTTCGGGTAGAGG
ATAATGGACCAGGGATTTCAGACGAAGATAAAAAGCGGATATTTGATCGATTCTACCGAGTGGATAAGGCGCGGACGCGT
CAAAAGGGTGGTTTTGGGTTAGGACTGTCCTTAGCCAAGCAAATCGTAGAAGCCTTTAATGGTACCATTACTGTTCGAGA
TAACAAGCCTAAAGGTGCTATTTTCGAGGTCAAACTAGCAACCAAGTCAGATAGTAAAAAGAAATCAGGTTCTAAATCAA
CAAAAAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae D39

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae R6

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae TIGR4

60.802

98.249

0.597
  ciaH Streptococcus mutans UA159

50.569

96.061

0.486

Multiple sequence alignment