Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EL079_RS08820 Genome accession   NZ_LR134283
Coordinates   1769370..1769663 (+) Length   97 a.a.
NCBI ID   WP_003032294.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC10713     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1764370..1774663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL079_RS08785 (NCTC10713_01797) - 1764424..1764783 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  EL079_RS08790 (NCTC10713_01798) glnA 1764822..1766168 (+) 1347 WP_003032299.1 type I glutamate--ammonia ligase -
  EL079_RS08795 (NCTC10713_01799) - 1766356..1766721 (+) 366 WP_003032307.1 DUF1033 family protein -
  EL079_RS08800 (NCTC10713_01800) comYA 1766791..1767732 (+) 942 WP_003032308.1 competence type IV pilus ATPase ComGA Machinery gene
  EL079_RS08805 (NCTC10713_01801) comYB 1767674..1768696 (+) 1023 WP_037582505.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL079_RS08810 (NCTC10713_01802) comYC 1768693..1769010 (+) 318 WP_003026997.1 competence type IV pilus major pilin ComGC Machinery gene
  EL079_RS08815 (NCTC10713_01803) comYD 1768970..1769398 (+) 429 WP_050791305.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL079_RS08820 (NCTC10713_01804) comGE/cglE 1769370..1769663 (+) 294 WP_003032294.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL079_RS08825 (NCTC10713_01805) comGF/cglF 1769647..1770084 (+) 438 WP_003032293.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL079_RS08830 (NCTC10713_01806) comGG 1770065..1770391 (+) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  EL079_RS08835 (NCTC10713_01807) comYH 1770476..1771429 (+) 954 WP_003032282.1 class I SAM-dependent methyltransferase Machinery gene
  EL079_RS08840 (NCTC10713_01808) - 1771476..1772675 (+) 1200 WP_003032291.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10941.89 Da        Isoelectric Point: 10.8025

>NTDB_id=1120058 EL079_RS08820 WP_003032294.1 1769370..1769663(+) (comGE/cglE) [Streptococcus anginosus strain NCTC10713]
MGNLRKQRVRGTILLEALLALAVFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIKVRVETSQQ
GIQIYHGRELILDVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1120058 EL079_RS08820 WP_003032294.1 1769370..1769663(+) (comGE/cglE) [Streptococcus anginosus strain NCTC10713]
ATGGGAAATTTAAGAAAACAACGCGTTAGAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAAACAAAGCAAAGTCATCTGACAATGAATGGTATTAAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAGATTTATCATGGAAGGGAACTAATTCTTGATGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae D39

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae R6

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae TIGR4

52.632

97.938

0.515
  comGE/cglE Streptococcus mitis NCTC 12261

51.579

97.938

0.505
  comGE/cglE Streptococcus mitis SK321

51.579

97.938

0.505
  comYE Streptococcus mutans UA140

43.434

100

0.443
  comYE Streptococcus mutans UA159

43.434

100

0.443

Multiple sequence alignment