Detailed information NTG1120060

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: EL079_RS08835
• Genome accession: NZ_LR134283
• Coordinates: 1770476..1771429 (+)
• Length: 317 a.a.
• NCBI ID: WP_003032282.1
• Uniprot ID: A0A448AK79
• Organism: Streptococcus anginosus strain NCTC10713
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1765476..1776429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL079_RS08795 (NCTC10713_01799)	-	1766356..1766721 (+)	366	WP_003032307.1	DUF1033 family protein	-
EL079_RS08800 (NCTC10713_01800)	comYA	1766791..1767732 (+)	942	WP_003032308.1	competence type IV pilus ATPase ComGA	Machinery gene
EL079_RS08805 (NCTC10713_01801)	comYB	1767674..1768696 (+)	1023	WP_037582505.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL079_RS08810 (NCTC10713_01802)	comYC	1768693..1769010 (+)	318	WP_003026997.1	competence type IV pilus major pilin ComGC	Machinery gene
EL079_RS08815 (NCTC10713_01803)	comYD	1768970..1769398 (+)	429	WP_050791305.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL079_RS08820 (NCTC10713_01804)	comGE/cglE	1769370..1769663 (+)	294	WP_003032294.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL079_RS08825 (NCTC10713_01805)	comGF/cglF	1769647..1770084 (+)	438	WP_003032293.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL079_RS08830 (NCTC10713_01806)	comGG	1770065..1770391 (+)	327	WP_018543596.1	competence type IV pilus minor pilin ComGG	-
EL079_RS08835 (NCTC10713_01807)	comYH	1770476..1771429 (+)	954	WP_003032282.1	class I SAM-dependent methyltransferase	Machinery gene
EL079_RS08840 (NCTC10713_01808)	-	1771476..1772675 (+)	1200	WP_003032291.1	acetate kinase	-
EL079_RS08845 (NCTC10713_01809)	glmS	1773064..1774878 (+)	1815	WP_022524764.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36123.92 Da
• Isoelectric Point: 4.2586

>NTDB_id=1120060 EL079_RS08835 WP_003032282.1 1770476..1771429(+) (comYH) [Streptococcus anginosus strain NCTC10713]
MNFEKIEQTYMLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDNIATRYEVASRQEHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKTWLQKHAQIVAMIALPEALFGNAAYAKTIFVLQKQEEQAVQLFVYALSDLRDQDDLLEFSEKFQNWSRESEI

Nucleotide

• Length: 954 bp

>NTDB_id=1120060 EL079_RS08835 WP_003032282.1 1770476..1771429(+) (comYH) [Streptococcus anginosus strain NCTC10713]
ATGAATTTTGAAAAAATTGAACAGACCTATATGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAATAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGACTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCAGTGCGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAACATTGCGACGCGCTATGAAGTGGCTAGTAGACAGGAGCATACTTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTGCTGAAAACTTGGCTGCAAAAGCATGCCCAGATAGTTGCGATGATTGCATTGCCAGAAGCACTTTTTGGAAA
TGCCGCTTATGCCAAGACAATTTTTGTGCTGCAAAAGCAAGAAGAACAAGCTGTTCAACTGTTTGTTTATGCTTTGTCTG
ATTTGCGAGATCAGGACGATTTATTGGAATTTAGCGAAAAGTTTCAAAATTGGAGCAGAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-299)

3D structure

• AlphaFold DB: A0A448AK79

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.27	99.369	0.609
comYH	Streptococcus mutans UA159	60.952	99.369	0.606