Detailed information NTG1120018

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: EL079_RS04130
• Genome accession: NZ_LR134283
• Coordinates: 837724..839076 (-)
• Length: 450 a.a.
• NCBI ID: WP_003032751.1
• Uniprot ID: A0A2I1UXL3
• Organism: Streptococcus anginosus strain NCTC10713
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 832724..844076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL079_RS04115 (NCTC10713_00867)	rnc	835462..836160 (-)	699	WP_003032757.1	ribonuclease III	-
EL079_RS04120	-	836553..836910 (-)	358	Protein_806	YbaN family protein	-
EL079_RS04125 (NCTC10713_00868)	vicX	836919..837722 (-)	804	WP_003032665.1	MBL fold metallo-hydrolase	Regulator
EL079_RS04130 (NCTC10713_00869)	micB	837724..839076 (-)	1353	WP_003032751.1	cell wall metabolism sensor histidine kinase VicK	Regulator
EL079_RS04135 (NCTC10713_00870)	micA	839069..839770 (-)	702	WP_003025150.1	response regulator YycF	Regulator
EL079_RS04140 (NCTC10713_00871)	-	840064..840405 (-)	342	WP_003032667.1	hypothetical protein	-
EL079_RS04145 (NCTC10713_00872)	-	840432..841745 (-)	1314	WP_003032712.1	glycosyltransferase family 4 protein	-
EL079_RS04150 (NCTC10713_00873)	-	841747..842745 (-)	999	WP_022524413.1	glycosyltransferase family 4 protein	-
EL079_RS04155 (NCTC10713_00874)	ccpA	842925..843929 (-)	1005	WP_003032767.1	catabolite control protein A	Regulator

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51376.62 Da
• Isoelectric Point: 4.6876

>NTDB_id=1120018 EL079_RS04130 WP_003032751.1 837724..839076(-) (micB) [Streptococcus anginosus strain NCTC10713]
MIDNIRQFIVSKDFVFVLLILGFILVITLLSLENRRDNIRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide

• Length: 1353 bp

>NTDB_id=1120018 EL079_RS04130 WP_003032751.1 837724..839076(-) (micB) [Streptococcus anginosus strain NCTC10713]
ATGATTGATAATATTAGACAATTTATTGTATCAAAAGACTTTGTATTTGTTTTACTTATTTTAGGGTTCATCTTGGTGAT
TACCTTGCTTTCCTTGGAAAATAGGCGAGACAATATTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGCCTGTCGAGTATTTTATCCTATATGACGGACGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATCAATGATATGGCGACCAAGCAGTTGGGGGTCAAAGAATCCGAAG
CACGAAAGATGAATATCTTAAAACTGCTAGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAATCTGG
CTTTATTTCAGGGCTGGTTGCGGTGCTGCACGATACAACGGAGCAGGAAAAAGAGGAGCGTGAGCGAAGACTGTTTGTTT
CGAATGTCAGTCACGAATTACGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCACTAGATGAAGGTGCCTTATCA
GAACCAGTCGCACCGGATTTCATCAAGGTTTCATTAGACGAGACCAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTACGAAATTATCCGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAAATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCGATTTCAGATGAAGGCTTAGGAATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCAAGAAGTCGCGCACAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAGCATAACGGATTTATCTGGGCAAAGAGCGAGTACGGCAAAGGCTCGACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

3D structure

• AlphaFold DB: A0A2I1UXL3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	81.093	97.556	0.791
vicK	Streptococcus mutans UA159	71.883	90.889	0.653