Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL078_RS04935 Genome accession   NZ_LR134282
Coordinates   963740..965065 (-) Length   441 a.a.
NCBI ID   WP_024344056.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 958740..970065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS04910 (NCTC8140_00991) - 959294..960349 (-) 1056 WP_080651031.1 BMP family lipoprotein -
  EL078_RS04915 (NCTC8140_00992) deoC 960538..961203 (-) 666 WP_021142326.1 deoxyribose-phosphate aldolase -
  EL078_RS04920 (NCTC8140_00993) - 961706..962296 (-) 591 WP_126437853.1 class I SAM-dependent methyltransferase -
  EL078_RS04925 (NCTC8140_00994) coaA 962410..963330 (+) 921 WP_126437854.1 type I pantothenate kinase -
  EL078_RS04930 (NCTC8140_00995) rpsT 963406..963657 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  EL078_RS04935 (NCTC8140_00996) ciaH 963740..965065 (-) 1326 WP_024344056.1 sensor histidine kinase Regulator
  EL078_RS04940 (NCTC8140_00997) ciaR 965055..965729 (-) 675 WP_024344055.1 response regulator transcription factor Regulator
  EL078_RS04945 (NCTC8140_00998) - 965882..968425 (-) 2544 WP_126437855.1 M1 family metallopeptidase -
  EL078_RS04950 (NCTC8140_00999) phoU 968634..969287 (-) 654 WP_024344053.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50148.05 Da        Isoelectric Point: 7.5433

>NTDB_id=1119978 EL078_RS04935 WP_024344056.1 963740..965065(-) (ciaH) [Streptococcus equinus strain NCTC8140]
MLNNIQKKLSTGTFSHFFHFFAVFTGIFVIMTIIILQIMRYGLYSSVDTTLQNAANNASDYVTRTMERSDSIQSDNTINE
SGKNKSSSNDGLSNVSVLLYDCNGKIVNALDAFIQFGSLTTSVNDDKIGEISEEKMTTIFGQTEKYHVLTVRVYSSDYPT
IQYATFLISVRQLDEANERYVTITITVMVIFWIISILASVYLANWTRKPILESYEKQKRFVENASHELRTPLAVLQNRLE
SLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIHPSTFNEIFENYQMIAHENNKKFTAHNLA
NRPIKSDKTLLKQLMTILFDNAIKYTGDDGVIEFTIKTTERQTILTIADNGPGVSDADKQKIFDRFYRVDKARTRQQGGF
GLGLSLAKQIVDALKGDIQVKDNKPKGTIFEVRFNRHNFGK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1119978 EL078_RS04935 WP_024344056.1 963740..965065(-) (ciaH) [Streptococcus equinus strain NCTC8140]
ATGCTGAATAATATACAGAAAAAATTATCAACGGGGACTTTCTCACACTTTTTCCATTTTTTTGCTGTGTTTACAGGGAT
TTTCGTTATTATGACAATTATTATCCTGCAAATCATGCGATATGGTTTATATTCTTCTGTCGACACGACGTTACAAAACG
CAGCTAATAATGCCAGTGATTACGTTACGAGAACGATGGAGAGAAGTGATTCGATTCAATCTGATAATACGATTAATGAG
TCAGGAAAAAATAAATCGAGTTCAAATGATGGATTGAGTAATGTTAGTGTCCTTTTGTATGATTGCAACGGTAAAATAGT
TAATGCTTTAGATGCCTTTATTCAATTTGGCTCACTAACGACGAGTGTTAATGATGATAAAATCGGTGAAATAAGCGAAG
AGAAGATGACTACGATTTTCGGTCAAACTGAAAAGTATCACGTCTTGACTGTCAGAGTTTATAGTAGTGATTATCCAACA
ATTCAATACGCAACCTTTCTAATTAGCGTTCGTCAGCTTGACGAGGCAAATGAAAGGTATGTGACAATTACTATTACAGT
TATGGTTATCTTTTGGATTATTTCAATTTTAGCGAGTGTTTATCTTGCAAACTGGACTCGTAAACCGATTCTTGAAAGTT
ATGAGAAACAGAAACGCTTTGTTGAGAATGCCAGTCATGAGTTGAGAACGCCGCTTGCTGTTTTGCAAAATCGTCTTGAA
AGTTTGTTTAGACGTCCAGATGCAACAATTTTAGATAATAGCGAAAGTATTGCTGCAAGTCTTGATGAAGTGCGAAATAT
GCGTATTCTGACAACAAATCTTTTAAATCTTGCTAGACGTGATGATGGTTTGAAAGTTGAATTGGAAGAGATTCATCCAT
CAACCTTTAACGAGATTTTTGAAAATTATCAGATGATTGCTCACGAAAATAACAAAAAGTTTACTGCACACAATTTAGCT
AATCGTCCGATAAAATCAGATAAGACTCTTTTGAAACAACTAATGACTATTTTATTTGATAATGCCATTAAGTACACTGG
TGATGATGGTGTTATTGAATTTACCATTAAAACAACAGAACGCCAAACTATTTTAACTATTGCTGATAACGGACCTGGTG
TTAGTGATGCCGATAAGCAGAAGATTTTTGATCGCTTTTACCGTGTCGACAAGGCAAGGACGCGCCAACAAGGTGGATTT
GGTTTGGGTTTGTCTCTAGCGAAGCAAATTGTTGATGCTTTGAAGGGTGATATTCAGGTTAAAGATAACAAACCAAAAGG
AACTATTTTTGAAGTTCGTTTCAACAGACATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(217-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.447

98.413

0.585
  ciaH Streptococcus pneumoniae Rx1

51.835

98.866

0.512
  ciaH Streptococcus pneumoniae D39

51.835

98.866

0.512
  ciaH Streptococcus pneumoniae R6

51.835

98.866

0.512
  ciaH Streptococcus pneumoniae TIGR4

51.835

98.866

0.512

Multiple sequence alignment