Detailed information NTG1119971

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL078_RS03065
• Genome accession: NZ_LR134282
• Coordinates: 568345..570576 (+)
• Length: 743 a.a.
• NCBI ID: WP_126437690.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC8140
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 563345..575576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL078_RS03035 (NCTC8140_00608)	-	563920..564582 (+)	663	WP_231997673.1	AraC family ligand binding domain-containing protein	-
EL078_RS09365	-	564595..564786 (+)	192	Protein_522	helix-turn-helix domain-containing protein	-
EL078_RS03040 (NCTC8140_00609)	-	564796..565686 (+)	891	WP_126437688.1	ROK family protein	-
EL078_RS03045 (NCTC8140_00610)	-	565701..565976 (-)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
EL078_RS03050 (NCTC8140_00611)	-	565951..566712 (-)	762	WP_074450932.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EL078_RS03055 (NCTC8140_00612)	-	566831..567577 (+)	747	WP_024344274.1	lysophospholipid acyltransferase family protein	-
EL078_RS03060 (NCTC8140_00613)	comEA	567672..568352 (+)	681	WP_126437689.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL078_RS03065 (NCTC8140_00614)	comEC/celB	568345..570576 (+)	2232	WP_126437690.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL078_RS03070 (NCTC8140_00615)	-	570682..571260 (+)	579	WP_126437691.1	HD domain-containing protein	-
EL078_RS03075 (NCTC8140_00616)	-	571272..571994 (+)	723	WP_231997674.1	CYTH domain-containing protein	-
EL078_RS03080 (NCTC8140_00617)	holA	572046..573083 (+)	1038	WP_164554306.1	DNA polymerase III subunit delta	-
EL078_RS03085 (NCTC8140_00618)	sodA	573180..573791 (+)	612	WP_039698404.1	superoxide dismutase SodA	-
EL078_RS03090 (NCTC8140_00619)	-	573897..574622 (+)	726	WP_126437693.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83972.57 Da
• Isoelectric Point: 9.3169

>NTDB_id=1119971 EL078_RS03065 WP_126437690.1 568345..570576(+) (comEC/celB) [Streptococcus equinus strain NCTC8140]
MIKHFPIKPIQLAFLLILVYYFCFLKVFWCIVLLLLALICLWKNYGSKKLWQTLIILMCFASFISFKNQQAEQADKVSPV
HLSKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYALKSEKEQQFFKSLNQTLVLSGEIDLEKATPQRNFGGFDYRTYLNH
EGIYRIGNLSSIVGMRRQTSLTLVERLHDLRRKAIVSIQQNFPAPMQHYMTGLLFGYLDKSFDEMSDIYTSLGIIHLFAL
SGMQVGFFVGVFRYFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVVRSLIQSGLGNIGVKRLDNLALTMMILFCIMPN
FLLTTEGILSFAYAFILSFIDFEELESYQKKIVECLAISLGSLPILIYFFSVFQPMSILLTAIFSLAFDTLMLPVLSMVF
LLSPLVRLSIFNSFFIVLEDVIKLTMNFLGGPIVFGKPSIGILVFLLFSLGVLYDYRQKRKVMIFLVSLVALLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGRTLLIDVGGKVSFSQKEGWQERLSDSNADRTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEVLVSQGSLTKPDFLAKLQAMKTKVRVVSAGDSLPIMGSSLQVLYPIRVGDGSNNDSVVLYGKLLGK
NFLFTGDLEEEGEREVMATYPNLPVDVLKAGHHGSKGSSSPAFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTF
YRTDQQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=1119971 EL078_RS03065 WP_126437690.1 568345..570576(+) (comEC/celB) [Streptococcus equinus strain NCTC8140]
TTGATTAAACATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTCTCGTTTATTATTTTTGCTTTTTGAAGGT
CTTTTGGTGCATAGTCCTCCTTTTATTAGCCCTGATCTGCTTATGGAAAAACTACGGTTCTAAAAAATTGTGGCAAACCT
TGATAATTCTGATGTGCTTTGCTAGTTTTATTAGTTTTAAAAATCAGCAAGCAGAGCAAGCTGACAAAGTATCGCCAGTT
CATTTATCAAAAATCCAGATGATTCCAGACACGATTTCGGTCAATGGTGACTTGCTGTCTTTTCGAGGAAAGGAGGCTGG
ACAGACTTATCAGGTCTTTTATGCTTTGAAGTCAGAAAAGGAGCAGCAATTTTTTAAAAGTCTTAATCAAACGCTTGTCT
TGTCTGGTGAGATTGACTTGGAGAAAGCAACGCCTCAGCGTAATTTTGGTGGGTTTGACTATCGTACTTACCTGAATCAT
GAAGGTATTTATCGCATTGGGAATCTTTCTTCAATTGTTGGGATGAGACGTCAAACTTCTTTGACTTTGGTTGAGCGACT
GCATGATTTGCGACGAAAAGCAATTGTTAGCATCCAGCAAAATTTTCCAGCACCCATGCAGCATTATATGACTGGGCTTT
TGTTTGGTTATCTGGATAAATCTTTTGATGAGATGAGCGATATTTACACAAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCCGGCATGCAGGTTGGCTTTTTTGTCGGTGTTTTTCGCTATTTCTTTTTGCGACTAGGCTTAAGGCGTGATTATGTTGA
CATTCTTCAAATCCCTTTTTCGCTTGTATATGCTGGTCTGACAGGGTTTTCAGTGTCAGTTGTCCGAAGTCTCATTCAGT
CAGGTTTAGGCAATATTGGCGTTAAGCGACTTGATAATCTTGCTTTGACCATGATGATTCTTTTCTGTATTATGCCTAAT
TTCTTGCTGACAACGGAAGGCATTTTGTCATTTGCTTATGCCTTTATCTTAAGTTTTATTGATTTTGAGGAACTTGAAAG
TTATCAGAAGAAAATTGTAGAATGCTTGGCAATTTCATTAGGGAGCTTACCAATTTTGATTTACTTTTTTTCAGTTTTTC
AACCGATGTCCATTCTTTTGACAGCTATTTTTTCATTGGCATTTGATACGCTTATGTTGCCGGTCTTGTCAATGGTTTTC
TTGCTTTCGCCACTCGTGAGATTATCAATTTTTAATAGCTTTTTTATCGTTTTAGAAGATGTGATAAAACTGACCATGAA
TTTCCTTGGTGGTCCGATTGTTTTTGGCAAACCAAGTATTGGTATTTTGGTATTCCTATTATTTAGCTTGGGTGTTCTTT
ATGATTATAGGCAGAAAAGGAAAGTTATGATTTTTCTTGTCAGCTTAGTAGCTCTGCTATTTTTCCAAATCAAGCATCCG
CTGGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAAGGGCGTACGCTGTT
AATTGATGTCGGAGGAAAAGTGAGCTTTAGCCAAAAAGAAGGCTGGCAAGAGCGCTTGTCTGACAGCAATGCAGATCGAA
CCTTGATTCCTTATCTCAATAGCCGTGGCGTTGGAAAAATTGACCAGCTGGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAGTTTTGGTTAGTCAAGGAAGTTTGACAAAGCCAGATTT
TTTGGCAAAATTACAAGCCATGAAAACCAAAGTTCGCGTAGTTTCTGCTGGAGATAGTTTGCCGATTATGGGAAGTAGCT
TGCAAGTGCTCTACCCTATTAGAGTTGGCGATGGTTCTAATAATGATTCGGTGGTGTTATATGGCAAGCTTCTAGGTAAA
AATTTTCTGTTTACAGGAGATTTGGAAGAAGAAGGTGAGCGTGAGGTGATGGCGACTTATCCTAATTTGCCAGTTGATGT
TTTAAAAGCGGGACACCATGGCTCAAAAGGGTCATCAAGCCCGGCATTTCTAGCTCATATTTCACCGCAAATTGCTTTGA
TTTCTGCTGGACAAAATAACCGCTACAAACATCCTCACCAAGAAACGCTTGAACGTTTCCGAGCACAAAACATGACCTTT
TACCGCACAGACCAACAAGGTGCTATCCGCTTTCGAGGCTTAAACCACTGGAAAATTGAGACGGTGAGGTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-696)

• Competence protein (Competence) (213-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	52.022	99.865	0.52
comEC/celB	Streptococcus mitis NCTC 12261	51.752	99.865	0.517
comEC/celB	Streptococcus pneumoniae TIGR4	51.009	100	0.51
comEC/celB	Streptococcus pneumoniae Rx1	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae D39	50.471	100	0.505
comEC/celB	Streptococcus pneumoniae R6	50.471	100	0.505
comEC	Lactococcus lactis subsp. cremoris KW2	47.376	100	0.474