Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL071_RS00995 Genome accession   NZ_LR134265
Coordinates   182292..182981 (-) Length   229 a.a.
NCBI ID   WP_115356636.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NCTC8184     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 177292..187981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS00975 (NCTC8184_00187) dnaI 178095..178997 (-) 903 WP_000843626.1 primosomal protein DnaI -
  EL071_RS00980 (NCTC8184_00188) - 178994..180169 (-) 1176 WP_000074512.1 DnaD domain protein -
  EL071_RS00985 (NCTC8184_00189) nrdR 180169..180648 (-) 480 WP_001203682.1 transcriptional regulator NrdR -
  EL071_RS00990 (NCTC8184_00190) - 180797..182302 (-) 1506 WP_115356637.1 HAMP domain-containing histidine kinase -
  EL071_RS00995 (NCTC8184_00191) covR 182292..182981 (-) 690 WP_115356636.1 response regulator transcription factor Regulator
  EL071_RS01000 (NCTC8184_00192) - 183216..183749 (-) 534 WP_000927543.1 YceD family protein -
  EL071_RS01005 (NCTC8184_00193) htpX 183854..184744 (-) 891 WP_000966817.1 zinc metalloprotease HtpX -
  EL071_RS01010 (NCTC8184_00194) - 184765..185319 (-) 555 WP_115356635.1 LemA family protein -
  EL071_RS01015 (NCTC8184_00195) rsmG 185447..186160 (+) 714 WP_000188792.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL071_RS01020 (NCTC8184_00196) - 186175..187554 (+) 1380 WP_000680112.1 potassium transporter TrkG -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26546.57 Da        Isoelectric Point: 4.8894

>NTDB_id=1119490 EL071_RS00995 WP_115356636.1 182292..182981(-) (covR) [Streptococcus agalactiae strain NCTC8184]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAEKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYNVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1119490 EL071_RS00995 WP_115356636.1 182292..182981(-) (covR) [Streptococcus agalactiae strain NCTC8184]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTGAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CAATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.039

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.228

99.563

0.659
  vicR Streptococcus mutans UA159

45.455

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.432

Multiple sequence alignment