Detailed information NTG1118962

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL020_RS04175
• Genome accession: NZ_LR134203
• Coordinates: 789689..791923 (+)
• Length: 744 a.a.
• NCBI ID: WP_061407386.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC11436
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 784689..796923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL020_RS04150 (NCTC11436_00864)	-	785431..787008 (+)	1578	WP_020916419.1	DEAD/DEAH box helicase	-
EL020_RS04155 (NCTC11436_00865)	-	787049..787324 (-)	276	WP_020916420.1	GIY-YIG nuclease family protein	-
EL020_RS04160 (NCTC11436_00866)	-	787299..788060 (-)	762	WP_020916421.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EL020_RS04165 (NCTC11436_00867)	-	788176..788922 (+)	747	WP_126402417.1	lysophospholipid acyltransferase family protein	-
EL020_RS04170 (NCTC11436_00868)	-	789019..789699 (+)	681	WP_020916423.1	helix-hairpin-helix domain-containing protein	-
EL020_RS04175 (NCTC11436_00869)	comEC/celB	789689..791923 (+)	2235	WP_061407386.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL020_RS04180 (NCTC11436_00870)	holA	791988..793025 (+)	1038	WP_126402418.1	DNA polymerase III subunit delta	-
EL020_RS04185 (NCTC11436_00871)	-	793120..793731 (+)	612	WP_020916426.1	superoxide dismutase	-
EL020_RS04190 (NCTC11436_00872)	-	793833..794558 (+)	726	WP_043894998.1	YebC/PmpR family DNA-binding transcriptional regulator	-
EL020_RS04195 (NCTC11436_00873)	queA	794609..795637 (-)	1029	WP_020916428.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
EL020_RS04200 (NCTC11436_00874)	-	795801..796307 (+)	507	WP_058833169.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84165.55 Da
• Isoelectric Point: 8.6739

>NTDB_id=1118962 EL020_RS04175 WP_061407386.1 789689..791923(+) (comEC/celB) [Streptococcus lutetiensis strain NCTC11436]
MLIKHFPVKPIQLAFLLILLYYFCFSKGIGCLMFLLLALLFLWQQYGWKAWYQVSLCLAFFAIFFLTKANQTEQASQAAP
TQLAKIQMIPDTISVNGDLLSFRGKEAGQTYQVFYILKSEKEQEFFKNLNQTMLLSGQVDLEEATPQRNFGGFDYRTYLK
HEGIYRIANLSSITEIRQQSSLSFFERLHELRRQAIVSIQRNFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFA
LSGMQVGFFVALFRFIILRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLAFTLMTLFILMP
NFLLTTGGILSFTYAFILSFIDFDELSHYQKILTECFAISLGSLPVLLYFFSVFQPLSLLLTAIFSLAFDTLILPVLTFV
FLLSPLVKITALNPFFVFLETIIKFSKSLIGTPLVFGRPSLGILLLLLLIIGLLYDCYRHKKVAIFLFSIIALLFFQIKH
PLENEVTVVDIGQGDSILVRDVKGQTLLIDVGGKVRFSEKKSWQKRLADSNAERTLIPYLKSRGIGKIDQLVLTHTDTDH
MGDMLEVAKELKIGQVLVSPGSLTKPDFVVKLRQMKTPVHAVSAGDNLPIMGSHLQVLYPNAVGDGGNNDSVVLYGNLLG
KNFLFTGDLEEEGEEQMMATYPNLPVDVLKAGHHGSKGSSSPEFLDHISPQMALISAGQNNRYKHPHQETLDRFQNQNMT
IYRTDQQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=1118962 EL020_RS04175 WP_061407386.1 789689..791923(+) (comEC/celB) [Streptococcus lutetiensis strain NCTC11436]
CTGTTGATTAAGCATTTCCCTGTCAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAA
AGGGATTGGGTGTTTGATGTTTCTCTTGCTAGCTTTGCTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTATCAGG
TTTCACTGTGTTTGGCTTTTTTTGCGATATTTTTCCTGACTAAGGCTAATCAGACAGAACAGGCTTCTCAAGCGGCGCCA
ACTCAGCTAGCAAAAATACAGATGATTCCAGATACGATTTCGGTTAATGGTGATTTGTTATCTTTTCGAGGGAAGGAGGC
TGGGCAGACTTACCAAGTTTTTTATATCTTGAAGTCAGAAAAAGAGCAGGAATTTTTTAAAAATCTTAATCAAACAATGC
TTTTATCAGGGCAGGTGGATCTAGAAGAGGCAACGCCACAACGGAATTTTGGTGGTTTTGATTACCGCACTTACCTTAAA
CATGAAGGCATTTATCGGATTGCTAATCTTTCTTCGATTACTGAAATAAGACAGCAGAGCTCTTTAAGTTTTTTTGAACG
ACTACATGAACTTAGAAGACAGGCGATTGTCAGTATTCAAAGGAATTTTCCTGCTCCCATGCAACATTACATGACTGGCC
TTTTGTTTGGATATTTGGATAAGTCTTTTGATGAGATGAGTGATGTTTATACTAGTTTAGGGATTATTCATCTTTTTGCT
CTGTCTGGTATGCAGGTAGGCTTTTTTGTGGCACTTTTTCGTTTTATTATTTTACGTCTTGGGTTACGGCGAGATTATGT
GGATATACTGCAAATCCCGTTTTCACTTGTATATGCTGGCTTGACAGGCTTTTCGGTATCAGTGATTCGTAGTTTAATTC
AGTCTGCCTTTGCAAATCTTGGTATTAAAAAATTAGATAATCTTGCCTTTACTTTAATGACCCTTTTTATTTTGATGCCA
AATTTCCTGCTAACAACAGGAGGAATTCTTTCTTTTACCTACGCTTTCATCCTGAGTTTTATTGATTTTGATGAGCTTAG
TCATTATCAAAAAATCCTTACAGAATGTTTTGCGATTTCGCTGGGAAGTTTACCGGTTTTGCTATATTTCTTCTCAGTAT
TTCAACCTTTGTCGCTGCTTTTAACAGCTATTTTTTCACTAGCTTTTGATACGCTTATCTTACCTGTTTTGACCTTTGTT
TTTCTTTTATCACCTCTGGTTAAAATTACCGCGTTAAATCCATTTTTTGTTTTTTTGGAAACTATCATCAAATTTAGTAA
GTCGCTGATTGGCACACCACTTGTTTTTGGCAGACCAAGTCTAGGAATTTTGTTGCTATTACTTTTAATAATAGGACTTC
TCTATGACTGTTATCGACACAAAAAAGTGGCCATTTTCCTTTTTAGCATAATAGCTTTGCTATTTTTCCAAATCAAGCAT
CCGCTCGAAAACGAAGTGACGGTGGTTGACATTGGGCAGGGAGATAGCATTTTGGTGCGAGATGTAAAGGGGCAGACGCT
GTTAATTGATGTCGGAGGAAAAGTGAGGTTTAGTGAGAAAAAATCGTGGCAAAAGCGCTTAGCTGATAGCAATGCTGAGC
GGACATTGATTCCTTATCTGAAAAGTCGAGGAATTGGTAAAATTGATCAGTTAGTTTTGACGCACACGGATACCGACCAT
ATGGGCGATATGCTGGAAGTCGCAAAAGAGCTGAAAATTGGTCAAGTCCTGGTGAGTCCAGGAAGTCTCACAAAGCCAGA
TTTTGTGGTTAAACTTCGACAAATGAAGACGCCAGTTCACGCAGTTTCTGCAGGAGATAACTTGCCAATTATGGGAAGTC
ACTTGCAGGTGCTTTATCCGAATGCTGTTGGTGATGGTGGAAATAATGATTCTGTGGTGCTTTATGGTAATCTTCTGGGT
AAGAATTTCTTGTTTACTGGAGACTTGGAAGAAGAGGGCGAAGAGCAGATGATGGCAACTTATCCCAATCTGCCAGTCGA
TGTCTTAAAAGCAGGACATCACGGTTCAAAAGGGTCATCGAGCCCAGAATTTCTAGATCACATTTCACCACAAATGGCTT
TGATTTCCGCAGGGCAAAATAACCGTTATAAACACCCTCACCAAGAAACACTTGATCGTTTTCAAAATCAAAATATGACC
ATTTACCGCACAGACCAACAAGGTGCTATCCGTTTTAGAGGATTAAACCACTGGAAAATTGAAACGGTGAGGTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-175)

• Competence protein (Competence) (214-455)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-686)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	50.943	99.731	0.508
comEC/celB	Streptococcus mitis NCTC 12261	50.943	99.731	0.508
comEC/celB	Streptococcus pneumoniae TIGR4	50.067	99.866	0.5
comEC/celB	Streptococcus pneumoniae Rx1	49.529	99.866	0.495
comEC/celB	Streptococcus pneumoniae D39	49.529	99.866	0.495
comEC/celB	Streptococcus pneumoniae R6	49.529	99.866	0.495
comEC	Lactococcus lactis subsp. cremoris KW2	47.46	100	0.477