Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL020_RS01205 Genome accession   NZ_LR134203
Coordinates   237297..237989 (-) Length   230 a.a.
NCBI ID   WP_058832790.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 232297..242989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS01185 (NCTC11436_00242) dnaI 233101..234003 (-) 903 WP_020917355.1 primosomal protein DnaI -
  EL020_RS01190 (NCTC11436_00243) - 234014..235165 (-) 1152 WP_126402337.1 DnaD domain protein -
  EL020_RS01195 (NCTC11436_00244) nrdR 235152..235646 (-) 495 WP_006532915.1 transcriptional regulator NrdR -
  EL020_RS01200 (NCTC11436_00245) - 235828..237297 (-) 1470 WP_058832789.1 HAMP domain-containing histidine kinase -
  EL020_RS01205 (NCTC11436_00246) covR 237297..237989 (-) 693 WP_058832790.1 response regulator transcription factor Regulator
  EL020_RS01210 (NCTC11436_00247) - 238240..238776 (-) 537 WP_058814197.1 YceD family protein -
  EL020_RS01215 (NCTC11436_00248) htpX 238918..239817 (-) 900 WP_020917360.1 zinc metalloprotease HtpX -
  EL020_RS01220 (NCTC11436_00249) - 239930..240481 (-) 552 WP_020917361.1 LemA family protein -
  EL020_RS01225 (NCTC11436_00250) rsmG 240775..241488 (+) 714 WP_020917362.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  EL020_RS01230 (NCTC11436_00251) - 241554..242927 (+) 1374 WP_058832791.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26358.34 Da        Isoelectric Point: 4.8466

>NTDB_id=1118936 EL020_RS01205 WP_058832790.1 237297..237989(-) (covR) [Streptococcus lutetiensis strain NCTC11436]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVEANGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQAKEGQAKEGLLGLRLNPQNRSAMRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1118936 EL020_RS01205 WP_058832790.1 237297..237989(-) (covR) [Streptococcus lutetiensis strain NCTC11436]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTTGTGTCTTTAGAATTACAACATGAGGGGTA
TTCAGTAGTTGTTGAGGCAAATGGACGTTTAGGGCTTCAAACAGCATTGGATGATGATTTTGATTTGATCCTATTAGATT
TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGCTTGGAAAAAGACACATCAATTATCATGATGACT
GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTTGACCGTGGAGCAGATGATTACATTGTAAAACCATTTGCTATTGA
AGAATTACTGGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGCAAAAGAAGGTCAAGCAAAAG
AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCGGCAATGCGTGGAGATGATGAAATTTCATTAACAAAACGT
GAATACGACTTGTTGAGCGTGCTTCTTTCAAATGTTAATCGCGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG
TTATGATACAGACATCGAAACAAATGTCGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

76.623

100

0.77
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417

Multiple sequence alignment