Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ELZ62_RS03810 Genome accession   NZ_LR134168
Coordinates   735663..736880 (+) Length   405 a.a.
NCBI ID   WP_126507584.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC11394     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 730663..741880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ62_RS03790 (NCTC11394_00753) corC 731627..732526 (-) 900 WP_126507582.1 CNNM family magnesium/cobalt transport protein CorC -
  ELZ62_RS03795 (NCTC11394_00754) ampD 733158..733712 (-) 555 WP_110432055.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ELZ62_RS03800 (NCTC11394_00755) pilA 733826..734275 (+) 450 WP_110432056.1 prepilin peptidase-dependent pilin Machinery gene
  ELZ62_RS03805 (NCTC11394_00756) pilB 734272..735666 (+) 1395 WP_126507583.1 GspE/PulE family protein Machinery gene
  ELZ62_RS03810 (NCTC11394_00757) pilC 735663..736880 (+) 1218 WP_126507584.1 type II secretion system F family protein Machinery gene
  ELZ62_RS03815 (NCTC11394_00758) pilD 736877..737569 (+) 693 WP_041175037.1 A24 family peptidase Machinery gene
  ELZ62_RS03820 (NCTC11394_00759) rho 737625..738887 (-) 1263 WP_015701557.1 transcription termination factor Rho -
  ELZ62_RS03825 (NCTC11394_00760) metJ 739135..739452 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  ELZ62_RS03830 (NCTC11394_00761) cueR 739466..739852 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  ELZ62_RS03835 (NCTC11394_00762) - 739929..740135 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  ELZ62_RS03840 (NCTC11394_00763) - 740221..740427 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  ELZ62_RS03845 (NCTC11394_00764) - 740501..740707 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46063.15 Da        Isoelectric Point: 9.6411

>NTDB_id=1118685 ELZ62_RS03810 WP_126507584.1 735663..736880(+) (pilC) [Haemophilus influenzae strain NCTC11394]
MTKKLFYYQASNALNQKQKGSIIADTKQQAHFQLINRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIVLNEWLEQLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFFLFYNFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1118685 ELZ62_RS03810 WP_126507584.1 735663..736880(+) (pilC) [Haemophilus influenzae strain NCTC11394]
ATGACTAAAAAACTCTTTTATTATCAAGCTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCACACTTTCAATTAATAAACCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCCACGTTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTGTACTCAATGAATGGCTTGAACAGCTACTCCAATCCATTGAGTCAGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACTCAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CGGGAAAACTTTCCGTTGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATTATGTTGTACCCATCAATGGTGTTAGGCATTTCACTATTACTAACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCGGAGTTACCAACAATAACCGCAATATTGCTCTCAATATCTAATTTCCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTTTTCTATTTTATAACTTCTATCTAAAACGCCAAACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCATTCCGCTTAATCAAGCGCTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTTCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTGGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Haemophilus influenzae 86-028NP

96.305

100

0.965
  pilC Glaesserella parasuis strain SC1401

39

98.765

0.385

Multiple sequence alignment