Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   NJ8700_RS10405 Genome accession   NZ_CP009230
Coordinates   2190083..2190727 (-) Length   214 a.a.
NCBI ID   WP_005701806.1    Uniprot ID   -
Organism   Aggregatibacter aphrophilus NJ8700     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2185083..2195727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NJ8700_RS10395 (NJ8700_10615) - 2187639..2188484 (+) 846 WP_005701808.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  NJ8700_RS10400 (NJ8700_10620) gorA 2188592..2189962 (+) 1371 WP_005701807.1 glutathione-disulfide reductase -
  NJ8700_RS10405 (NJ8700_10625) crp 2190083..2190727 (-) 645 WP_005701806.1 cAMP-activated global transcriptional regulator CRP Regulator
  NJ8700_RS10410 (NJ8700_10630) - 2190765..2190983 (-) 219 WP_005701805.1 YheU family protein -
  NJ8700_RS10415 (NJ8700_10635) slmA 2191007..2191591 (-) 585 Protein_2025 nucleoid occlusion factor SlmA -
  NJ8700_RS10420 (NJ8700_10640) dut 2191606..2192061 (-) 456 WP_005701802.1 dUTP diphosphatase -
  NJ8700_RS10425 (NJ8700_10645) coaBC 2192110..2193309 (-) 1200 WP_012771967.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  NJ8700_RS10430 (NJ8700_10655) radC 2193487..2194146 (+) 660 WP_005704497.1 DNA repair protein RadC Machinery gene
  NJ8700_RS10435 (NJ8700_10660) rpmB 2194357..2194593 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  NJ8700_RS10440 (NJ8700_10665) rpmG 2194605..2194775 (+) 171 WP_005544948.1 50S ribosomal protein L33 -
  NJ8700_RS10445 (NJ8700_10670) mutM 2194845..2195660 (+) 816 WP_005701798.1 DNA-formamidopyrimidine glycosylase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24091.72 Da        Isoelectric Point: 7.3995

>NTDB_id=111834 NJ8700_RS10405 WP_005701806.1 2190083..2190727(-) (crp) [Aggregatibacter aphrophilus NJ8700]
MQEQNAQATQPTDPTLDWFLSHCHIHKYPSKSTLINAGEKAETLYYLIQGSVSVMVKDEDGKEMILTYLGQGDFFGEAGL
FEEGQLRSAWIKAKSACEVAEISYRKFRQLIQANPEILMYLTAQLARRLQNTSRQVSNLAFLDVTGRIAQTLLNLAKMPE
AMTHPDGMQIKITRQEIGQMVGCSRETVGRILKMLEDQHLISAHGKTIVVYGTR

Nucleotide


Download         Length: 645 bp        

>NTDB_id=111834 NJ8700_RS10405 WP_005701806.1 2190083..2190727(-) (crp) [Aggregatibacter aphrophilus NJ8700]
GTGCAGGAACAAAACGCACAAGCTACACAACCCACGGATCCAACGTTGGACTGGTTTTTATCACATTGCCATATTCATAA
ATATCCATCTAAAAGCACATTAATCAACGCCGGCGAAAAAGCCGAAACACTTTATTATTTAATCCAAGGCTCCGTCTCCG
TTATGGTGAAAGACGAAGATGGAAAAGAGATGATTCTCACTTATTTAGGCCAAGGGGATTTCTTTGGTGAAGCAGGCTTA
TTTGAAGAAGGTCAGCTTCGTTCTGCATGGATCAAAGCCAAAAGCGCCTGTGAAGTGGCTGAAATCTCGTATCGCAAATT
CCGCCAACTCATTCAGGCTAACCCTGAAATTTTAATGTATTTAACTGCGCAACTTGCCAGACGCTTACAAAACACCTCGC
GCCAAGTGAGCAATTTGGCATTCTTAGATGTCACCGGTCGCATTGCGCAAACCTTATTAAACTTAGCCAAAATGCCGGAA
GCCATGACACACCCTGATGGTATGCAAATTAAAATCACCCGCCAGGAAATTGGTCAAATGGTGGGTTGCTCACGCGAAAC
CGTTGGCCGAATTTTAAAAATGTTGGAAGATCAACATCTCATATCCGCTCACGGCAAGACTATTGTCGTTTACGGCACCC
GTTAA

Domains

Predicted by InterProScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(146-210)

Cyclic nucleotide-binding domain (cNMP_binding)

(27-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

81.731

97.196

0.794
  crp Vibrio cholerae strain A1552

81.281

94.86

0.771
  crp Acinetobacter baumannii D1279779

48.718

91.121

0.444

Multiple sequence alignment