Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ELZ51_RS02065 Genome accession   NZ_LR134094
Coordinates   378732..379418 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 373732..384418
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS02040 (NCTC4669_00431) ktrB 373840..375216 (-) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -
  ELZ51_RS02045 (NCTC4669_00432) rsmG 375300..376013 (-) 714 WP_115246663.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ELZ51_RS02050 (NCTC4669_00433) - 376166..376723 (+) 558 WP_126425867.1 LemA family protein -
  ELZ51_RS02055 (NCTC4669_00434) htpX 376768..377661 (+) 894 WP_003049732.1 zinc metalloprotease HtpX -
  ELZ51_RS02060 (NCTC4669_00435) - 377928..378461 (+) 534 WP_164549244.1 YceD family protein -
  ELZ51_RS02065 (NCTC4669_00436) covR 378732..379418 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  ELZ51_RS02070 (NCTC4669_00437) - 379428..380927 (+) 1500 WP_126425871.1 HAMP domain-containing histidine kinase -
  ELZ51_RS02075 (NCTC4669_00438) nrdR 381134..381628 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  ELZ51_RS02080 (NCTC4669_00439) - 381612..382790 (+) 1179 WP_126425873.1 DnaD domain protein -
  ELZ51_RS02085 (NCTC4669_00440) dnaI 382791..383693 (+) 903 WP_003049744.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=1118267 ELZ51_RS02065 WP_003049736.1 378732..379418(+) (covR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1118267 ELZ51_RS02065 WP_003049736.1 378732..379418(+) (covR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
CGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTAGAAACTGCCTTAGAAAAGGATTTTGACTTAATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATTATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGGTTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCAATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment