Detailed information NTG1117814

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: ELZ47_RS03980
• Genome accession: NZ_LR134002
• Coordinates: 770745..772094 (+)
• Length: 449 a.a.
• NCBI ID: WP_125331413.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 765745..777094

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS03955 (NCTC10904_00777)	-	766384..767076 (+)	693	WP_185758705.1	AAA family ATPase	-
ELZ47_RS03960 (NCTC10904_00778)	thrS	767073..769016 (+)	1944	WP_126435316.1	threonine--tRNA ligase	-
ELZ47_RS03965 (NCTC10904_00779)	-	769108..769512 (-)	405	WP_125331412.1	hypothetical protein	-
ELZ47_RS03970	-	769622..769804 (-)	183	Protein_727	amino acid ABC transporter permease	-
ELZ47_RS03975 (NCTC10904_00780)	micA	770051..770752 (+)	702	WP_002894937.1	response regulator YycF	Regulator
ELZ47_RS03980 (NCTC10904_00781)	micB	770745..772094 (+)	1350	WP_125331413.1	cell wall metabolism sensor histidine kinase VicK	Regulator
ELZ47_RS03985 (NCTC10904_00782)	vicX	772104..772904 (+)	801	WP_125331414.1	MBL fold metallo-hydrolase	Regulator
ELZ47_RS03990 (NCTC10904_00783)	-	772996..773355 (+)	360	WP_004186130.1	YbaN family protein	-
ELZ47_RS03995 (NCTC10904_00784)	rnc	773477..774175 (+)	699	WP_002903151.1	ribonuclease III	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 50961.83 Da
• Isoelectric Point: 4.3896

>NTDB_id=1117814 ELZ47_RS03980 WP_125331413.1 770745..772094(+) (micB) [Streptococcus sanguinis strain NCTC 10904]
MIEAIKQFVVSADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDDI

Nucleotide

• Length: 1350 bp

>NTDB_id=1117814 ELZ47_RS03980 WP_125331413.1 770745..772094(+) (micB) [Streptococcus sanguinis strain NCTC 10904]
ATGATTGAAGCAATTAAACAATTTGTGGTTTCTGCGGATTTTGTCTTTGCAATCATTATTATCGGCTTCATTGTAGTTGT
TGCCTTGCTTTTATTGGAAAATCGCCGTGATAACCAAAAGCTTGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GTGACTATTCTGAAGTGCTGGACATGCAAGGGAGTCCAGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGTCTGACACATGAAAACCTTGAGCAAGAAACTAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGAGT
GCTTGCGACCAACCGCCGGGGGCAGATTATCACTATCAACGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGCGGGACTTGATTACCAATGTTCCTGAG
CTGACGATAGATTCTCAGGATGAAAATGGTGAGTACTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTCATTTCTGGTTTGGTAGCTGTCTTGCATGATACGACAGAGCAGGACAAGGAAGAACGGGAGCGTCGCCTCTTTGTCT
CCAACGTCAGCCATGAGTTGCGGACTCCGCTGACCAGTGTTAAGTCCTATCTGGAAGCCTTGGATGAGGGAGCCTTGTCT
GAGCCAGTAGCACCGGACTTTGTCAAGGTATCGCTCAATGAAACCAACCGCATGATGCGGATGGTGACGGACTTGCTCAG
TCTGTCCCGTATTGACAACGAGACCAGTCATCTGGAAGTGGAGCTGACGAATTTCACAGCCTTCATAACTTTTATCCTCA
ATCGCTTTGACAAGATAAAGAATCAAGACGAGACCAAGAAATACGAGATTATCCGTGATTATCCCATTACACCGATTTGG
GTGGAGATTGATACAGATAAGCTGACTCAGGTGATTGATAATATCATGAACAATGCCATCAAGTATTCGCCGGATGGTGG
AACCATTACTGTTTCCATCAAGACAACTGATGAGCAGTTGATTCTTTCGATTGCGGATGAAGGTCTGGGAATTCCCAAGC
AGGACTTGCCTAAGATTTTTGACCGCTTTTATCGAGTGGACAAGGCACGCAGCCGTGCCCAAGGCGGAACGGGTCTGGGG
CTGGCTATTGCCAAGGAAATTATCAAGCAGCATCAGGGATTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGCGTCCGCGATGACGACTGGGATAATGAAGATGATATATAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.588	97.773	0.768
vicK	Streptococcus mutans UA159	70.72	89.755	0.635