Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EW029_RS05925 Genome accession   NZ_LR130513
Coordinates   1202456..1203328 (+) Length   290 a.a.
NCBI ID   WP_000620187.1    Uniprot ID   A0AAE2ZTP9
Organism   Staphylococcus aureus strain BPH2900 isolate BPH2900     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1197456..1208328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW029_RS05905 sucC 1197570..1198736 (+) 1167 WP_001020802.1 ADP-forming succinate--CoA ligase subunit beta -
  EW029_RS05910 sucD 1198758..1199666 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  EW029_RS05915 - 1199893..1201011 (+) 1119 WP_001041672.1 LysM peptidoglycan-binding domain-containing protein -
  EW029_RS05920 fmhC 1201039..1202283 (+) 1245 WP_000673440.1 FemA/FemB family glycyltransferase FmhC -
  EW029_RS05925 dprA 1202456..1203328 (+) 873 WP_000620187.1 DNA-processing protein DprA Machinery gene
  EW029_RS05930 topA 1203502..1205577 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  EW029_RS05935 trmFO 1205733..1207040 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33609.00 Da        Isoelectric Point: 9.5142

>NTDB_id=1116854 EW029_RS05925 WP_000620187.1 1202456..1203328(+) (dprA) [Staphylococcus aureus strain BPH2900 isolate BPH2900]
MIRLFLLKLYWSHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=1116854 EW029_RS05925 WP_000620187.1 1202456..1203328(+) (dprA) [Staphylococcus aureus strain BPH2900 isolate BPH2900]
TTGATTAGACTATTTTTGCTTAAGTTATACTGGTCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

99.31

100

0.993
  dprA Staphylococcus aureus N315

98.966

100

0.99
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

38.163

97.586

0.372
  dprA/cilB/dalA Streptococcus pneumoniae D39

38.163

97.586

0.372
  dprA/cilB/dalA Streptococcus pneumoniae R6

38.163

97.586

0.372
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

38.163

97.586

0.372
  dprA/cilB/dalA Streptococcus mitis SK321

37.809

97.586

0.369

Multiple sequence alignment