Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   EW024_RS01410 Genome accession   NZ_LR130237
Coordinates   257088..259067 (+) Length   659 a.a.
NCBI ID   WP_021299351.1    Uniprot ID   A0A660A5X6
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 252088..264067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS01390 sufU 252134..252613 (+) 480 WP_011528251.1 Fe-S cluster assembly sulfur transfer protein SufU -
  EW024_RS01395 sufB 252606..254024 (+) 1419 WP_146707954.1 Fe-S cluster assembly protein SufB -
  EW024_RS01400 - 254176..255357 (-) 1182 WP_011528252.1 D-alanyl-D-alanine carboxypeptidase family protein -
  EW024_RS01405 pbp3 255525..256757 (-) 1233 WP_021299357.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  EW024_RS01410 amiA 257088..259067 (+) 1980 WP_021299351.1 peptide ABC transporter substrate-binding protein Regulator
  EW024_RS01415 amiC 259132..260634 (+) 1503 WP_011017334.1 ABC transporter permease Regulator
  EW024_RS01420 amiD 260634..261560 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  EW024_RS01425 amiE 261569..262639 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  EW024_RS01430 amiF 262632..263555 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  EW024_RS09565 - 263593..263676 (-) 84 Protein_229 IS3 family transposase -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72426.97 Da        Isoelectric Point: 5.1964

>NTDB_id=1116549 EW024_RS01410 WP_021299351.1 257088..259067(+) (amiA) [Streptococcus pyogenes strain SP444 isolate SP444]
MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLV
PSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENYWD
AKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKK
DPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKLGDEWKDVN
LADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETSTHE
AQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDN
DARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGAFAWAGAKGPASVYYYKGMKLQDKPVTAKQFEKAKEKWMK
AKAKSNAKYAEKLADHVEK

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=1116549 EW024_RS01410 WP_021299351.1 257088..259067(+) (amiA) [Streptococcus pyogenes strain SP444 isolate SP444]
ATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGGTAATAAAAA
TGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATTATATTTTGA
CTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGTAATTTAGTA
CCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGTCTCTTGGTA
TACGGCTGATGGTGAAGAATATGCCCCAGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTGACGATAAAT
CAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTTAAAGAAGTT
GGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAAAACAACTTA
TAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCATCATCAATCC
TTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAACTACTGGGAT
GCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAAGAACTTTGA
CAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATGCTGATAACA
TTACTTACGGAATGTTGACTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAACACTAAGAAA
GACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAATTTGCTTTTGACCG
AGCGTCATTCCAAGCACAAACTGCAGGTCAAGATGCCAAAACAAAAGCCTTACGTAACATGCTTGTGCCACCAACTTTTG
TAACCGTTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGTGATGAATGGAAAGACGTTAAC
TTAGCTGATGCTCAAGATGGTTTCTATAATCCAGAAAAAGCAAAAGTTGAATTTGCAAAAGCCAAAGAAGCTTTGACAGC
TGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAGGCAAACGCAGCAACTGTTCAGGAAGCCCAGTCTT
TCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAAAATGTCATTGTCAATGTTCTTGAAACAGAAACATCAACTCACGAA
GCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATCATTTCATCATGGTGGGGACCAGACTACCAAGA
TCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGTGGATCTGTTATCCAAAAACTTGGAATCAAAGCAGGTCAAA
ATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACTTACCAAACTCTTCTTGATGAAGCAGCAGCAATTACAGACGACAAC
GATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAGTGCCGTAGATATTCCAGTTGTGGCATTGGG
TGGCACTCCTCGAGTTACTAAAGCCGTTCCATTTAGCGGTGCCTTTGCCTGGGCAGGTGCTAAAGGTCCTGCTTCTGTAT
ATTATTATAAAGGAATGAAACTTCAAGACAAACCTGTCACAGCAAAACAATTCGAAAAAGCAAAAGAAAAATGGATGAAA
GCAAAGGCTAAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(79-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A660A5X6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

51.131

100

0.514
  amiA3 Streptococcus thermophilus LMG 18311

50.226

100

0.505
  amiA3 Streptococcus thermophilus LMD-9

49.925

100

0.502

Multiple sequence alignment