Detailed information NTG1116488

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: EW021_RS00630
• Genome accession: NZ_LR130236
• Coordinates: 99562..100515 (+)
• Length: 317 a.a.
• NCBI ID: WP_010921802.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 5448 isolate 5448
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 94562..105515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EW021_RS00590	-	95389..95754 (+)	366	WP_002986560.1	DUF1033 family protein	-
EW021_RS00595	comYA	95847..96785 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
EW021_RS00600	comYB	96721..97755 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
EW021_RS00605	comYC	97757..98083 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
EW021_RS00610	comGD	98058..98486 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
EW021_RS00615	comGE	98443..98727 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
EW021_RS00620	comYF	98720..99154 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
EW021_RS00625	comGG	99138..99464 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
EW021_RS00630	comYH	99562..100515 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
EW021_RS00635	-	100574..101770 (+)	1197	WP_010921803.1	acetate kinase	-
EW021_RS00640	-	101957..102265 (+)	309	WP_010921804.1	hypothetical protein	-
EW021_RS00645	proC	102348..103118 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-
EW021_RS00650	pepA	103166..104233 (-)	1068	WP_010921806.1	glutamyl aminopeptidase	-
EW021_RS00660	-	104698..104982 (+)	285	WP_002992749.1	DUF4651 domain-containing protein	-
EW021_RS00665	-	104979..105296 (+)	318	WP_011285355.1	thioredoxin family protein	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36015.10 Da
• Isoelectric Point: 4.7205

>NTDB_id=1116488 EW021_RS00630 WP_010921802.1 99562..100515(+) (comYH) [Streptococcus pyogenes strain 5448 isolate 5448]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide

• Length: 954 bp

>NTDB_id=1116488 EW021_RS00630 WP_010921802.1 99562..100515(+) (comYH) [Streptococcus pyogenes strain 5448 isolate 5448]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTGTTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-288)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA159	65.823	99.685	0.656
comYH	Streptococcus mutans UA140	65.506	99.685	0.653