Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EQB46_RS10950 Genome accession   NZ_LR129843
Coordinates   2004663..2005325 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 180-2 isolate 180-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1999663..2010325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB46_RS10925 - 1999813..2000079 (-) 267 WP_001278167.1 Veg family protein -
  EQB46_RS10930 dnaB 2000081..2001433 (-) 1353 WP_000852486.1 replicative DNA helicase -
  EQB46_RS10935 rplI 2001477..2001929 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EQB46_RS10940 - 2001926..2003899 (-) 1974 WP_000715124.1 DHH family phosphoesterase -
  EQB46_RS10945 hpf 2004035..2004583 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EQB46_RS10950 comFC/cflB 2004663..2005325 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  EQB46_RS10955 comFA/cflA 2005322..2006620 (-) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  EQB46_RS10960 - 2006676..2007311 (+) 636 WP_000395739.1 YigZ family protein -
  EQB46_RS10965 cysK 2007596..2008516 (+) 921 WP_000029867.1 cysteine synthase A -
  EQB46_RS10975 - 2008755..2009129 (-) 375 Protein_2038 IS66 family transposase -
  EQB46_RS10980 - 2009102..2009389 (+) 288 Protein_2039 transposase -
  EQB46_RS10985 tnpB 2009544..2009867 (-) 324 WP_000973415.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=1116390 EQB46_RS10950 WP_000649971.1 2004663..2005325(-) (comFC/cflB) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1116390 EQB46_RS10950 WP_000649971.1 2004663..2005325(-) (comFC/cflB) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment