Detailed information NTG1116344

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EQB46_RS04845
• Genome accession: NZ_LR129843
• Coordinates: 889804..890757 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 180-2 isolate 180-2
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 884804..895757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB46_RS04820	rpmG	885547..885696 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
EQB46_RS04825	secG	885736..885969 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EQB46_RS04830	rnr	886071..888425 (+)	2355	WP_000654920.1	ribonuclease R	-
EQB46_RS04835	smpB	888388..888855 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
EQB46_RS04840	tehB	888871..889731 (+)	861	WP_000413769.1	SAM-dependent methyltransferase TehB	-
EQB46_RS04845	coiA	889804..890757 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
EQB46_RS04850	pepF	890776..892578 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
EQB46_RS04855	-	892580..893293 (+)	714	WP_000230399.1	O-methyltransferase	-
EQB46_RS04860	prsA	893360..894301 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EQB46_RS04865	-	894420..894761 (-)	342	Protein_926	transposase	-
EQB46_RS04875	-	895174..895269 (+)	96	Protein_927	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=1116344 EQB46_RS04845 WP_000495909.1 889804..890757(+) (coiA) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1116344 EQB46_RS04845 WP_000495909.1 889804..890757(+) (coiA) [Streptococcus pneumoniae strain 180-2 isolate 180-2]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435