Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   EQB41_RS09265 Genome accession   NZ_LR129840
Coordinates   1733367..1734026 (+) Length   219 a.a.
NCBI ID   WP_000565020.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1728367..1739026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS09245 - 1729004..1729900 (-) 897 WP_000825669.1 PEP phosphonomutase -
  EQB41_RS09250 - 1729903..1731165 (-) 1263 WP_127820840.1 PTS sugar transporter subunit IIC -
  EQB41_RS09255 - 1731445..1732623 (+) 1179 WP_000175875.1 ROK family transcriptional regulator -
  EQB41_RS09260 - 1732851..1733297 (-) 447 WP_000155418.1 GNAT family N-acetyltransferase -
  EQB41_RS09265 cclA/cilC 1733367..1734026 (+) 660 WP_000565020.1 prepilin peptidase Machinery gene
  EQB41_RS09270 - 1734078..1735226 (-) 1149 WP_127820841.1 XRE family transcriptional regulator -
  EQB41_RS09275 - 1735241..1735972 (-) 732 Protein_1763 hypothetical protein -
  EQB41_RS09280 - 1736192..1736302 (+) 111 Protein_1764 prepilin peptidase -
  EQB41_RS09285 trpA 1736274..1737050 (-) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  EQB41_RS09290 trpB 1737043..1738266 (-) 1224 WP_000331296.1 tryptophan synthase subunit beta -
  EQB41_RS09295 - 1738244..1738843 (-) 600 WP_000169907.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24869.01 Da        Isoelectric Point: 7.9575

>NTDB_id=1116206 EQB41_RS09265 WP_000565020.1 1733367..1734026(+) (cclA/cilC) [Streptococcus pneumoniae strain 4496 isolate 4496]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1116206 EQB41_RS09265 WP_000565020.1 1733367..1734026(+) (cclA/cilC) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTAGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872

Multiple sequence alignment