Detailed information NTG1115712

Bioinformatically predicted

Overview

• Name: pilQ
• Type: Machinery gene
• Locus tag: TTHNP4_RS01380
• Genome accession: NZ_LR027517
• Coordinates: 234953..237226 (-)
• Length: 757 a.a.
• NCBI ID: WP_124104239.1
• Uniprot ID: A0A3P4AN54
• Organism: Thermus thermophilus isolate TTHNAR1
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 229953..242226

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TTHNP4_RS01350 (TTHN1_00269)	-	229963..230316 (+)	354	WP_124104235.1	DUF4870 domain-containing protein	-
TTHNP4_RS01355 (TTHN1_00270)	-	230294..230671 (-)	378	WP_011173441.1	4'-phosphopantetheinyl transferase superfamily protein	-
TTHNP4_RS01360 (TTHN1_00271)	rsmF	230724..232094 (+)	1371	WP_124104236.1	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	-
TTHNP4_RS01365 (TTHN1_00272)	-	232140..233186 (-)	1047	WP_011228641.1	3-dehydroquinate synthase family protein	-
TTHNP4_RS01370 (TTHN1_00273)	-	233164..233718 (-)	555	WP_124104237.1	shikimate kinase	-
TTHNP4_RS01375 (TTHN1_00274)	aroC	233743..234894 (-)	1152	WP_124104238.1	chorismate synthase	-
TTHNP4_RS01380 (TTHN1_00275)	pilQ	234953..237226 (-)	2274	WP_124104239.1	secretin N-terminal domain-containing protein	Machinery gene
TTHNP4_RS14400 (TTHN1_00276)	pilW	237223..238113 (-)	891	WP_124104240.1	competence protein	Machinery gene
TTHNP4_RS01390 (TTHN1_00277)	pilO	238110..238691 (-)	582	WP_124104241.1	type 4a pilus biogenesis protein PilO	Machinery gene
TTHNP4_RS01395 (TTHN1_00278)	pilN	238681..239304 (-)	624	WP_011228637.1	competence protein	Machinery gene
TTHNP4_RS01400 (TTHN1_00279)	pilM	239297..240430 (-)	1134	WP_124104242.1	type IV pilus assembly protein PilM	Machinery gene
TTHNP4_RS01405 (TTHN1_00280)	-	240560..241564 (-)	1005	WP_124104243.1	homoisocitrate dehydrogenase	-
TTHNP4_RS01410 (TTHN1_00281)	-	241619..242110 (-)	492	WP_011173430.1	DUF5317 domain-containing protein	-

Sequence

Protein

• Length: 757 a.a.
• Molecular weight: 82568.66 Da
• Isoelectric Point: 5.3068

>NTDB_id=1115712 TTHNP4_RS01380 WP_124104239.1 234953..237226(-) (pilQ) [Thermus thermophilus isolate TTHNAR1]
MKSAWIRAAVIALAGLGAFALAGSFPEEPRFQAPVNLKVSESQVKAGQTLPLDVVLEALARSVGLQPLIYRAYDPSGDPA
KAQPPLPNIKLDFQGKPFREVWDLLFATYGAQYGLDYLFLPPDVVVVAPTQVITALVDAPSRTGAMERRPYLVGIPEAAY
RVAVQGQGGQVQVTSNVEAAKAWVQNDLLPFLSREAAGLNVNWIVVEEGGRLKAVLSVLATPEQHARFSDILQRAGIDFR
PLPALAQPKPRVEKTYTLTYATFPDLLAFLQSRLPEAQISVVPTNPQRAIVLATEEDHARLSELLKTADVPKTVRRVYAL
QNLTFREAQERLKPLLEKDLKGARLESLPGNPKALLLEAPEAEHALFAEILKALDVPPQAPEAPQEATLRRLYPLRYANA
EQVAPFLAREVPGIVVQTVPGQPILSVRGTERQLAEVESLLAQIDRAPEQGPPVFQRAYQLSNAKAVELAQVLQEALKAR
QAQNQGQQNQAPPTREATVVADPRTNTLIVTGTQEDLALVEGLIPKLDQPVPQVNLRVRIQEVQSNLTRSLGLKWNSIAG
GNVAASILDSGLSLIFDSTRSLAALNIMATLDALQQQGLSRALRDVNQTVLNNQTARLQSGETFFIRRVVEGNVERVPFD
IGLIVEVTPQITADGQILLNIRAEVSGNVQRNPVDGDVDRFTKQVVTTTLRVKDGETVVLGGLTSQESNQSQQGVPLLMD
IPLIGELFKQRTNERTDKELLVVITADILKETASANP

Nucleotide

• Length: 2274 bp

>NTDB_id=1115712 TTHNP4_RS01380 WP_124104239.1 234953..237226(-) (pilQ) [Thermus thermophilus isolate TTHNAR1]
ATGAAGAGCGCGTGGATCCGTGCGGCCGTGATCGCCCTCGCAGGGCTAGGGGCTTTTGCCCTTGCGGGGAGCTTTCCCGA
GGAGCCCCGCTTCCAGGCCCCGGTGAACCTCAAGGTCTCGGAATCCCAGGTCAAGGCGGGCCAGACCCTGCCCCTGGACG
TGGTCCTCGAGGCCCTGGCGCGAAGCGTGGGGCTCCAGCCCCTCATCTACCGGGCCTACGACCCGAGCGGGGACCCCGCC
AAGGCCCAGCCCCCCCTGCCCAACATCAAGCTGGACTTCCAGGGCAAGCCCTTCCGGGAGGTCTGGGACCTCCTCTTCGC
CACCTACGGGGCCCAGTACGGCCTGGACTACCTTTTCCTGCCCCCCGACGTGGTGGTGGTGGCCCCCACCCAGGTGATCA
CCGCCCTGGTGGACGCCCCGAGCCGCACGGGGGCCATGGAGCGTAGGCCCTACCTTGTAGGTATCCCCGAAGCGGCCTAC
CGGGTGGCGGTACAGGGACAGGGAGGGCAGGTCCAGGTCACCTCAAACGTGGAGGCGGCCAAGGCCTGGGTTCAGAACGA
CCTCCTCCCCTTCCTCTCCCGGGAGGCCGCGGGGCTCAACGTGAACTGGATCGTGGTGGAGGAGGGCGGGAGGCTCAAGG
CCGTCCTCTCCGTCCTCGCCACCCCCGAGCAACACGCCCGCTTCTCCGATATTCTGCAGCGGGCCGGGATTGACTTCCGC
CCCCTCCCCGCCCTGGCCCAGCCCAAGCCCCGGGTGGAGAAGACCTACACCCTCACCTACGCCACCTTCCCCGACCTCCT
CGCCTTCCTCCAGTCCCGCCTCCCCGAGGCCCAGATCAGCGTGGTCCCCACCAACCCCCAAAGGGCCATCGTCCTCGCCA
CCGAGGAGGACCACGCCCGCTTGAGCGAGCTTCTGAAGACGGCCGACGTCCCCAAGACCGTCCGCCGGGTCTACGCCCTG
CAGAACCTCACCTTCAGGGAGGCCCAGGAGCGCCTAAAGCCCCTCCTGGAAAAGGACCTCAAGGGGGCCCGCCTGGAGAG
CCTCCCCGGCAACCCCAAGGCCCTCCTCCTCGAGGCCCCCGAAGCGGAGCACGCCCTCTTCGCCGAGATCCTGAAGGCCC
TGGACGTCCCCCCCCAGGCCCCCGAAGCCCCCCAGGAGGCCACCTTGCGGCGCCTCTACCCCCTGCGCTACGCCAACGCC
GAGCAGGTGGCCCCCTTCCTCGCCCGGGAGGTGCCGGGCATCGTGGTGCAGACCGTGCCGGGACAACCCATCCTCTCCGT
GCGGGGCACGGAGAGGCAACTGGCCGAGGTGGAAAGCCTCCTCGCCCAGATTGACCGGGCCCCCGAGCAAGGCCCTCCCG
TGTTCCAGCGGGCCTACCAGCTCTCCAACGCCAAGGCGGTGGAGCTCGCCCAGGTGCTCCAGGAGGCGCTCAAGGCCCGG
CAGGCCCAGAACCAGGGCCAGCAGAACCAGGCCCCCCCCACCCGGGAGGCCACGGTGGTGGCCGACCCCAGGACCAACAC
CCTCATCGTCACCGGCACCCAGGAGGACCTCGCCCTGGTGGAGGGCCTCATCCCCAAGCTGGACCAGCCCGTGCCCCAGG
TGAACCTCAGGGTGCGCATCCAGGAGGTCCAGTCCAACCTGACCCGGAGCCTCGGCCTCAAGTGGAACAGCATCGCCGGC
GGCAACGTGGCGGCCAGCATCCTGGACTCGGGGCTTTCCCTCATCTTTGACTCCACGCGAAGCCTCGCCGCCCTCAACAT
CATGGCCACCCTGGACGCCCTGCAGCAACAGGGCCTCTCCCGGGCCCTCCGGGACGTGAACCAGACCGTCCTCAACAACC
AGACCGCCCGCCTGCAGTCCGGCGAGACCTTCTTCATCCGGCGGGTGGTGGAGGGGAACGTGGAGCGGGTGCCCTTTGAC
ATCGGCCTCATCGTGGAGGTCACGCCCCAGATCACCGCCGACGGCCAGATCCTCCTCAACATCAGGGCCGAGGTCTCGGG
GAACGTCCAGCGCAACCCCGTGGACGGGGACGTGGACCGCTTCACCAAGCAGGTGGTGACCACCACCCTCAGGGTCAAGG
ACGGGGAGACCGTGGTCCTCGGGGGCCTCACCTCCCAGGAGTCCAACCAGAGCCAGCAGGGGGTGCCCCTCCTCATGGAC
ATCCCCCTGATCGGCGAGCTCTTCAAGCAGCGGACGAACGAGCGCACCGACAAGGAGCTTCTGGTGGTGATCACCGCCGA
CATCCTCAAGGAGACGGCCTCGGCGAACCCCTAA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (391-450)

• Bacterial type II/III secretion system short domain (Secretin_N) (457-533)

• Bacterial type II and III secretion system protein (Secretin) (593-750)

3D structure

• AlphaFold DB: A0A3P4AN54

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilQ	Thermus thermophilus HB27	94.98	100	0.95