Detailed information NTG1114405

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AT689_RS08930
• Genome accession: NZ_LN831051
• Coordinates: 1687997..1688950 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain NCTC7465
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1682997..1693950

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT689_RS12615	-	1683487..1683582 (-)	96	Protein_1685	IS630 family transposase	-
AT689_RS08910 (ERS445053_01751)	-	1683995..1684336 (+)	342	Protein_1686	transposase	-
AT689_RS08915 (ERS445053_01752)	prsA	1684453..1685394 (-)	942	WP_000727933.1	peptidylprolyl isomerase PrsA	-
AT689_RS08920 (ERS445053_01753)	-	1685461..1686174 (-)	714	WP_000230399.1	O-methyltransferase	-
AT689_RS08925 (ERS445053_01754)	pepF	1686176..1687978 (-)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
AT689_RS08930 (ERS445053_01755)	coiA	1687997..1688950 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
AT689_RS08935 (ERS445053_01756)	tehB	1689023..1689883 (-)	861	WP_000413758.1	SAM-dependent methyltransferase TehB	-
AT689_RS08940 (ERS445053_01757)	smpB	1689899..1690366 (-)	468	WP_001051753.1	SsrA-binding protein SmpB	-
AT689_RS08945 (ERS445053_01758)	rnr	1690329..1692683 (-)	2355	WP_000654877.1	ribonuclease R	-
AT689_RS08950 (ERS445053_01759)	secG	1692785..1693018 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
AT689_RS08955	rpmG	1693058..1693207 (-)	150	WP_001809104.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=1114405 AT689_RS08930 WP_000495909.1 1687997..1688950(-) (coiA) [Streptococcus pneumoniae strain NCTC7465]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1114405 AT689_RS08930 WP_000495909.1 1687997..1688950(-) (coiA) [Streptococcus pneumoniae strain NCTC7465]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435