Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   AT689_RS05025 Genome accession   NZ_LN831051
Coordinates   926954..927613 (-) Length   219 a.a.
NCBI ID   WP_000565020.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 921954..932613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS05000 (ERS445053_00976) - 922134..922733 (+) 600 WP_000169907.1 phosphoribosylanthranilate isomerase -
  AT689_RS05005 (ERS445053_00977) trpB 922711..923934 (+) 1224 WP_000331296.1 tryptophan synthase subunit beta -
  AT689_RS05010 (ERS445053_00978) trpA 923927..924703 (+) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  AT689_RS11625 - 924675..924785 (-) 111 Protein_933 prepilin peptidase -
  AT689_RS05015 (ERS445053_00980) - 925005..925736 (+) 732 Protein_934 hypothetical protein -
  AT689_RS05020 (ERS445053_00981) - 925751..926902 (+) 1152 WP_000481760.1 XRE family transcriptional regulator -
  AT689_RS05025 (ERS445053_00982) cclA/cilC 926954..927613 (-) 660 WP_000565020.1 A24 family peptidase Machinery gene
  AT689_RS05030 (ERS445053_00983) - 927683..928129 (+) 447 WP_000155418.1 GNAT family N-acetyltransferase -
  AT689_RS05035 (ERS445053_00984) - 928357..929535 (-) 1179 WP_000175875.1 ROK family transcriptional regulator -
  AT689_RS05040 (ERS445053_00985) - 929815..931077 (+) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  AT689_RS05045 (ERS445053_00986) - 931080..931976 (+) 897 WP_000825669.1 PEP phosphonomutase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24869.01 Da        Isoelectric Point: 7.9575

>NTDB_id=1114389 AT689_RS05025 WP_000565020.1 926954..927613(-) (cclA/cilC) [Streptococcus pneumoniae strain NCTC7465]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1114389 AT689_RS05025 WP_000565020.1 926954..927613(-) (cclA/cilC) [Streptococcus pneumoniae strain NCTC7465]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTAGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872

Multiple sequence alignment