Detailed information NTG1114258

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: AT683_RS00050
• Genome accession: NZ_LN831035
• Coordinates: 15400..16521 (+)
• Length: 373 a.a.
• NCBI ID: WP_012055334.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain NCTC8143
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 10400..21521

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT683_RS00035 (ERS450003_00006)	leuC	10561..11970 (-)	1410	WP_011272333.1	3-isopropylmalate dehydratase large subunit	-
AT683_RS00040 (ERS450003_00007)	leuB	12147..13223 (-)	1077	WP_038440279.1	3-isopropylmalate dehydrogenase	-
AT683_RS00045 (ERS450003_00008)	leuA	13309..14856 (-)	1548	WP_038440280.1	2-isopropylmalate synthase	-
AT683_RS00050 (ERS450003_00009)	dprA	15400..16521 (+)	1122	WP_012055334.1	DNA-processing protein DprA	Machinery gene
AT683_RS00055 (ERS450003_00010)	yaaA	16574..17350 (+)	777	WP_005688368.1	peroxide stress protein YaaA	-
AT683_RS00060 (ERS450003_00011)	-	17343..17924 (+)	582	WP_005651586.1	hypothetical protein	-
AT683_RS00065 (ERS450003_00012)	pfkA	18020..18985 (+)	966	WP_005659252.1	6-phosphofructokinase	-
AT683_RS00070 (ERS450003_00013)	smpB	19224..19709 (+)	486	WP_005659251.1	SsrA-binding protein SmpB	-
AT683_RS00075 (ERS450003_00014)	fis	19804..20103 (-)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
AT683_RS00080 (ERS450003_00015)	dusB	20097..21077 (-)	981	WP_012055332.1	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41639.71 Da
• Isoelectric Point: 6.4124

>NTDB_id=1114258 AT683_RS00050 WP_012055334.1 15400..16521(+) (dprA) [Haemophilus influenzae strain NCTC8143]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNY
FSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=1114258 AT683_RS00050 WP_012055334.1 15400..16521(+) (dprA) [Haemophilus influenzae strain NCTC8143]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTACCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTCGCGTGGTCACAAAAAGAGGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAAACCGCAAACTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGGAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTCATTGTCATCAGGCTGTCGTT
AATATTCAAGGGCAAACTATTGCGGTCTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGTGCATTAGTCTCTGAATTTTTACCAAACCAAGCACCTATTGCTGCTAATTTTCCACGTC
GTAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACCGAAAAAAGCGGATCACTTATTACTGCA
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTAATTAAACAAGGTGCAATGTTGGTAGAAAATGCTAAAGATATTTTGGAAACCCTCTATCAACATTCAATCCATAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCTGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTACTCGCGTATTGGTTACACGCCTGTGAGCATTGATGATTTAGCGGAAGAATTTAACTTGAGTGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	99.196	100	0.992
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.617	100	0.44
dprA	Vibrio cholerae strain A1552	43.014	97.855	0.421
dprA	Legionella pneumophila strain ERS1305867	40.634	93.029	0.378