Detailed information NTG1113998

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: LACPI_RS10150
• Genome accession: NZ_LN774769
• Coordinates: 2093766..2094458 (-)
• Length: 230 a.a.
• NCBI ID: WP_047916201.1
• Uniprot ID: -
• Organism: Lactococcus piscium MKFS47
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2088766..2099458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LACPI_RS10135 (LACPI_1999)	-	2090126..2090467 (-)	342	WP_047916198.1	P-II family nitrogen regulator	-
LACPI_RS10140 (LACPI_2000)	-	2090505..2091743 (-)	1239	WP_047916199.1	ammonium transporter	-
LACPI_RS10145 (LACPI_2001)	-	2092007..2093500 (-)	1494	WP_047916200.1	HAMP domain-containing sensor histidine kinase	-
LACPI_RS10150 (LACPI_2002)	covR	2093766..2094458 (-)	693	WP_047916201.1	response regulator transcription factor	Regulator
LACPI_RS10155 (LACPI_2003)	gndA	2094642..2096063 (-)	1422	WP_047916202.1	NADP-dependent phosphogluconate dehydrogenase	-
LACPI_RS10160 (LACPI_2004)	-	2096321..2096857 (-)	537	WP_047916203.1	YceD family protein	-
LACPI_RS10165 (LACPI_2005)	-	2097029..2097964 (+)	936	WP_047914927.1	IS30 family transposase	-
LACPI_RS10170 (LACPI_2006)	-	2098093..2099028 (-)	936	WP_047916204.1	manganese-dependent inorganic pyrophosphatase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26776.54 Da
• Isoelectric Point: 5.2714

>NTDB_id=1113998 LACPI_RS10150 WP_047916201.1 2093766..2094458(-) (covR) [Lactococcus piscium MKFS47]
MVKKILIIEDEKQLARFVSLELEHEGYSVVVRHDGRSGLEAAMAQDWDMILLDLMLPELDGFEVARRLRNEKQTPITMMT
ARDSTMDKVAGLDIGADDYITKPFAIEELLARLRANFRRQDREIQKRKKTDGTTFRDLTINKKNRQVERGGEVIDLTKRE
YDLLTTLMKNVNDVVTREQLVQNVWGYDEGTETNVVDVYIRYLRNKLDQDGKDSYIQTVRGLGYMLRENN

Nucleotide

• Length: 693 bp

>NTDB_id=1113998 LACPI_RS10150 WP_047916201.1 2093766..2094458(-) (covR) [Lactococcus piscium MKFS47]
ATGGTAAAGAAAATTCTTATTATTGAAGATGAAAAACAATTAGCACGATTTGTGTCACTTGAACTAGAACATGAGGGGTA
CAGTGTTGTTGTACGTCATGATGGTCGTAGTGGTCTTGAAGCAGCGATGGCTCAAGATTGGGATATGATCCTCTTAGATT
TGATGTTACCTGAGTTAGACGGATTTGAAGTTGCCCGTCGTTTACGTAATGAGAAACAAACACCGATTACGATGATGACT
GCGCGCGATAGTACCATGGATAAAGTAGCTGGTCTTGACATTGGTGCAGATGACTACATTACGAAACCGTTTGCCATTGA
AGAATTACTGGCGCGTCTACGTGCTAATTTCCGTCGTCAAGATCGTGAAATTCAAAAGCGTAAAAAAACTGATGGGACAA
CCTTCCGTGATTTGACGATTAATAAAAAGAACCGTCAAGTAGAACGTGGTGGAGAAGTGATCGACTTGACAAAACGTGAG
TATGATTTATTGACGACACTGATGAAAAATGTCAACGATGTTGTGACGCGTGAACAACTTGTCCAAAACGTATGGGGATA
TGATGAAGGAACAGAGACAAACGTTGTTGATGTTTATATTCGTTACCTACGTAACAAATTAGATCAAGATGGTAAAGATT
CATATATTCAAACAGTTCGTGGTTTAGGCTACATGTTGCGTGAAAATAACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (151-226)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	75.664	98.261	0.743
covR	Streptococcus salivarius strain HSISS4	67.544	99.13	0.67
micA	Streptococcus pneumoniae Cp1015	43.777	100	0.443
vicR	Streptococcus mutans UA159	41.81	100	0.422