Detailed information NTG1113932

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LHA_RS13405
• Genome accession: NZ_LN681225
• Coordinates: 3019688..3020761 (+)
• Length: 357 a.a.
• NCBI ID: WP_045106986.1
• Uniprot ID: A0A0A8UWF4
• Organism: Legionella hackeliae strain ATCC 35250
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3014688..3025761

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LHA_RS13380 (LHA_2882)	-	3015399..3015887 (-)	489	WP_045106982.1	hypothetical protein	-
LHA_RS13385 (LHA_2883)	-	3015972..3016718 (-)	747	WP_045106983.1	CPBP family glutamic-type intramembrane protease	-
LHA_RS13390 (LHA_2884)	rsmB	3016708..3017997 (-)	1290	WP_045106984.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LHA_RS13395 (LHA_2885)	fmt	3017994..3018929 (-)	936	WP_045107600.1	methionyl-tRNA formyltransferase	-
LHA_RS13400 (LHA_2886)	def	3019009..3019518 (-)	510	WP_045106985.1	peptide deformylase	-
LHA_RS13405 (LHA_2887)	dprA	3019688..3020761 (+)	1074	WP_045106986.1	DNA-processing protein DprA	Machinery gene
LHA_RS13410 (LHA_2888)	-	3020761..3021189 (+)	429	WP_045106987.1	DUF494 family protein	-
LHA_RS13415 (LHA_2889)	topA	3021220..3023499 (+)	2280	WP_045106988.1	type I DNA topoisomerase	-
LHA_RS16835 (LHA_2890)	-	3023638..3023919 (+)	282	WP_158644251.1	nucleoside hydrolase	-
LHA_RS16840 (LHA_2891)	-	3024028..3024678 (+)	651	WP_102046658.1	nucleoside hydrolase	-
LHA_RS13425 (LHA_2892)	-	3024732..3025580 (-)	849	WP_045106989.1	GyrI-like domain-containing protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 38731.15 Da
• Isoelectric Point: 7.9735

>NTDB_id=1113932 LHA_RS13405 WP_045106986.1 3019688..3020761(+) (dprA) [Legionella hackeliae strain ATCC 35250]
MKNKPYLLALNKIPFVGPRTITKLLLKWPNLEELFRLSQQELEQAGIPSRMAQAIKTFNFKDIQLDLCWAEKSGHHLLTI
EDVNYPSLLKEIADPPAVLYAIGELSCLLQPSIAMVGSRKPSAIGGETARRFAMELATNQLTIVSGLALGIDAQAHEGCL
EVNGKTIAVLGTGIDFTYPRQHKILTAKISQTGLLLSEFPLKTPPMAGHFPRRNRIISGLSLATLVVEAAIKSGSLITAR
FALEQNRDVLAIPGSILNPQARGCHYLLQQGAKLVTSTQDIMDELNLDSKQVAQTNATLSLATDNKNLVKCIGFEITTVD
QIIARSGLGIEEVVSSLATLELEGIVKAIPGGYMRCA

Nucleotide

• Length: 1074 bp

>NTDB_id=1113932 LHA_RS13405 WP_045106986.1 3019688..3020761(+) (dprA) [Legionella hackeliae strain ATCC 35250]
ATGAAAAATAAGCCTTACCTGCTTGCTTTAAATAAAATACCGTTTGTGGGCCCCCGTACCATCACCAAGTTGCTATTAAA
ATGGCCCAATCTGGAAGAACTATTTCGTCTCTCACAACAAGAATTGGAGCAAGCTGGCATCCCCTCACGCATGGCTCAAG
CCATTAAAACATTTAATTTTAAAGACATTCAACTTGATTTGTGTTGGGCAGAAAAAAGCGGTCATCATTTACTGACGATT
GAAGATGTTAATTACCCCTCTTTATTAAAAGAAATTGCCGATCCTCCGGCAGTTCTTTATGCAATAGGCGAATTATCCTG
TCTTTTGCAGCCCAGCATCGCCATGGTGGGGAGTCGAAAACCCTCTGCGATTGGCGGTGAAACAGCACGTCGATTTGCCA
TGGAACTCGCGACGAATCAATTAACGATTGTCAGTGGCTTAGCCTTGGGAATTGATGCTCAAGCCCATGAAGGATGTCTA
GAAGTAAATGGCAAGACTATTGCTGTCTTAGGCACGGGAATTGATTTTACCTACCCTCGTCAACATAAGATATTAACGGC
AAAAATTAGCCAAACCGGGTTGTTATTAAGTGAATTTCCCTTAAAAACACCACCAATGGCTGGACATTTTCCACGCAGAA
ATCGTATAATAAGCGGTTTATCATTAGCCACATTGGTAGTTGAGGCAGCAATCAAAAGTGGTTCTTTGATCACAGCTCGA
TTTGCATTAGAGCAAAATCGGGATGTGCTGGCGATTCCAGGTTCTATTCTGAATCCACAAGCCAGAGGTTGTCACTATCT
TTTACAGCAAGGAGCTAAGTTAGTGACTTCGACGCAGGATATTATGGATGAGTTAAATCTGGATAGTAAGCAAGTCGCCC
AAACTAACGCAACACTATCCCTTGCCACGGATAACAAAAACCTAGTAAAGTGCATTGGCTTTGAAATCACAACCGTCGAT
CAAATCATTGCACGAAGCGGCTTAGGTATTGAAGAGGTGGTCAGCTCGCTGGCTACATTAGAATTAGAGGGTATTGTGAA
AGCAATCCCCGGTGGCTACATGAGGTGTGCGTAA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (297-352)

• DNA recombination-mediator protein A (DNA_processg_A) (70-276)

3D structure

• AlphaFold DB: A0A0A8UWF4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	63.585	100	0.636
dprA	Vibrio campbellii strain DS40M4	44.507	99.44	0.443
dprA	Glaesserella parasuis strain SC1401	40.761	100	0.42
dprA	Vibrio cholerae strain A1552	41.389	100	0.417
dprA	Haemophilus influenzae Rd KW20	41.742	93.277	0.389