Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H702_RS03135 Genome accession   NZ_AUZH01000012
Coordinates   167064..167756 (+) Length   230 a.a.
NCBI ID   WP_006532917.1    Uniprot ID   A0A380KNN3
Organism   Streptococcus equinus JB1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 162064..172756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H702_RS03110 (H702_03210) - 162130..163503 (-) 1374 WP_039696376.1 TrkH family potassium uptake protein -
  H702_RS03115 (H702_03215) rsmG 163579..164291 (-) 713 Protein_159 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H702_RS03120 (H702_03220) - 164581..165132 (+) 552 WP_039696377.1 LemA family protein -
  H702_RS03125 (H702_03225) htpX 165245..166144 (+) 900 WP_039696378.1 zinc metalloprotease HtpX -
  H702_RS03130 (H702_03230) - 166287..166823 (+) 537 WP_039696379.1 YceD family protein -
  H702_RS03135 (H702_03235) covR 167064..167756 (+) 693 WP_006532917.1 response regulator transcription factor Regulator
  H702_RS03140 (H702_03240) - 167756..169243 (+) 1488 WP_039696380.1 HAMP domain-containing sensor histidine kinase -
  H702_RS03145 (H702_03245) nrdR 169403..169897 (+) 495 WP_004233042.1 transcriptional regulator NrdR -
  H702_RS03150 (H702_03250) - 169884..171035 (+) 1152 WP_039696381.1 DnaD domain protein -
  H702_RS03155 (H702_03255) dnaI 171046..171948 (+) 903 WP_024343628.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26400.31 Da        Isoelectric Point: 4.7654

>NTDB_id=111305 H702_RS03135 WP_006532917.1 167064..167756(+) (covR) [Streptococcus equinus JB1]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=111305 H702_RS03135 WP_006532917.1 167064..167756(+) (covR) [Streptococcus equinus JB1]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTTGTGTCTTTAGAATTACAACATGAGGGGTA
TTCAGTAGTTGTTGAGACAAATGGACGTTTAGGGCTTCAAACTGCATTGGATGATGATTTTGATTTGATCCTATTAGATT
TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGTTTGGAAAAAGACACATCAATTATCATGATGACT
GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTTGACCGTGGAGCAGATGATTATATTGTAAAACCATTTGCTATTGA
AGAATTACTCGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGACAAAGAAGGTCAAGCAAAAG
AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCTGCAGTTCGTGGTGATGATGAAATTTCATTAACAAAACGT
GAATACGATTTGTTGAGCGTGCTTCTTTCAAACGTTAATCGTGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG
TTATGATACAGACATTGAAACAAATGTCGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KNN3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

76.087

100

0.761
  covR Lactococcus lactis subsp. lactis strain DGCC12653

64.192

99.565

0.639
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417
  vicR Streptococcus mutans UA159

41.558

100

0.417

Multiple sequence alignment