Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ACMCNI_RS06140 Genome accession   NZ_AP038791
Coordinates   1346798..1348186 (-) Length   462 a.a.
NCBI ID   WP_226691996.1    Uniprot ID   -
Organism   Rodentibacter sp. THUN1657     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1341798..1353186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMCNI_RS06120 (THUN1657_11730) yihA 1342916..1343533 (+) 618 WP_226692000.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACMCNI_RS06125 (THUN1657_11740) comM 1343739..1345268 (+) 1530 WP_226691999.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  ACMCNI_RS06130 (THUN1657_11750) nfuA 1345334..1345918 (-) 585 WP_226691998.1 Fe-S biogenesis protein NfuA -
  ACMCNI_RS06135 (THUN1657_11760) - 1346018..1346746 (-) 729 WP_226691997.1 double zinc ribbon domain-containing protein -
  ACMCNI_RS06140 (THUN1657_11770) comE 1346798..1348186 (-) 1389 WP_226691996.1 type IV pilus secretin PilQ Machinery gene
  ACMCNI_RS06145 (THUN1657_11780) - 1348195..1348581 (-) 387 WP_226691995.1 hypothetical protein -
  ACMCNI_RS06150 (THUN1657_11790) - 1348584..1349102 (-) 519 WP_226691994.1 hypothetical protein -
  ACMCNI_RS06155 (THUN1657_11800) - 1349099..1349614 (-) 516 WP_226691993.1 PilN domain-containing protein -
  ACMCNI_RS06160 (THUN1657_11810) comA 1349627..1350433 (-) 807 WP_226691992.1 competence protein ComA Machinery gene
  ACMCNI_RS06165 (THUN1657_11820) - 1350532..1353144 (+) 2613 WP_226691991.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 462 a.a.        Molecular weight: 50934.60 Da        Isoelectric Point: 7.7613

>NTDB_id=111244 ACMCNI_RS06140 WP_226691996.1 1346798..1348186(-) (comE) [Rodentibacter sp. THUN1657]
MKGEFKKCGLFFLCFCCAFSSMAEFKENQVFSIRLKQAPMVSSLQELALVQGTNLIIDDEIEGSLSLQLDKVDFDRILRS
VAKMKGLSLRVEDDIYYLGKRSTGETFATAYVETSQAVANEAFKAMKPSEPMLISRTVKLHFAKALEVMKSLTTGSGSLL
SAQGSIAFDDRSNLLIIQDEAKSVKNMLKLIAELDKPIEQIAIEARIVTISDESLKELGVRWGIFTPTENTHRVSGSLAA
NGFANLTDNLNVNFATNSTPAGSLALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTSG
KNDTQTVEFREAVLGLEVTPHISKDNNILLDLLVSQNSPGKRVSYGQQNNEVVSIDKQEINTQVFAKDGETIVLGGVFHD
TITKAVDKVPVLGDIPLVKRLFSKESERHQKRELVIFVTPHILKQGETLESLKQKTKSRKGK

Nucleotide


Download         Length: 1389 bp        

>NTDB_id=111244 ACMCNI_RS06140 WP_226691996.1 1346798..1348186(-) (comE) [Rodentibacter sp. THUN1657]
ATGAAAGGTGAGTTTAAAAAGTGCGGTCTATTTTTTCTGTGTTTTTGTTGTGCTTTTTCATCAATGGCGGAATTTAAGGA
AAATCAAGTTTTTTCCATTCGATTAAAACAAGCCCCGATGGTTTCAAGCTTGCAAGAATTAGCCTTAGTGCAAGGAACGA
ATTTGATTATCGATGATGAAATCGAGGGTTCGCTTTCCTTGCAATTAGACAAGGTGGATTTTGATCGCATACTGCGCTCG
GTGGCAAAAATGAAAGGGCTGTCGTTACGTGTGGAAGACGATATTTATTATTTGGGAAAACGAAGTACGGGTGAAACTTT
TGCAACAGCCTATGTGGAAACATCACAAGCGGTCGCTAATGAAGCTTTTAAGGCAATGAAACCGAGCGAGCCTATGTTAA
TCAGCCGTACCGTCAAATTACATTTCGCCAAAGCTCTAGAGGTGATGAAGTCCCTTACAACGGGAAGCGGTTCGCTGTTA
TCTGCGCAAGGGAGCATTGCTTTTGATGATCGCAGCAATTTATTGATTATTCAAGATGAAGCAAAATCCGTCAAAAATAT
GCTGAAACTGATTGCAGAGTTAGATAAACCGATTGAACAAATCGCTATTGAAGCACGCATTGTTACGATTAGCGATGAAA
GTTTAAAAGAATTAGGCGTACGTTGGGGGATTTTCACTCCCACGGAAAATACACACAGAGTAAGTGGGAGTTTAGCGGCA
AATGGTTTTGCTAATTTAACGGATAATCTCAATGTGAATTTCGCCACCAATTCCACACCGGCAGGTTCTCTTGCTTTACA
GGTGGCAAAGATTAACGGACGATTATTAGACTTGGAATTGACCGCACTTGAACGTGAAAATAATGTAGAAATTATCGCCA
GCCCAAGGTTACTGACGACTAACAAGAAAAGTGCAAGCATTAAACAGGGAACGGAAATTCCCTATGTAGTGACAAGCGGC
AAAAATGATACGCAAACGGTGGAATTTCGTGAGGCCGTGCTAGGGCTTGAGGTCACGCCGCATATTTCCAAAGATAACAA
TATTTTGTTGGATTTGTTAGTTAGCCAAAATTCACCGGGTAAGCGAGTATCTTACGGGCAGCAAAACAATGAAGTGGTAT
CTATCGACAAACAAGAAATCAATACGCAAGTTTTTGCGAAAGACGGGGAAACGATTGTATTAGGCGGTGTGTTTCACGAT
ACTATCACCAAAGCGGTGGATAAAGTACCGGTGCTGGGGGATATTCCGTTGGTGAAACGATTGTTTAGTAAAGAAAGTGA
ACGCCATCAAAAGCGTGAGTTGGTTATTTTTGTTACACCTCATATTCTCAAGCAAGGCGAAACCCTGGAAAGCTTGAAGC
AAAAAACGAAAAGCAGGAAGGGAAAGTAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(282-444)

Bacterial type II/III secretion system short domain (Secretin_N)

(136-200)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

71.15

99.784

0.71
  comE Haemophilus influenzae 86-028NP

70.499

99.784

0.703
  comE Glaesserella parasuis strain SC1401

53.708

96.32

0.517
  pilQ Vibrio campbellii strain DS40M4

41.002

95.022

0.39
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.244

93.939

0.387
  pilQ Vibrio cholerae strain A1552

41.244

93.939

0.387

Multiple sequence alignment