Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACN076_RS09250 Genome accession   NZ_CP184836
Coordinates   1887279..1887938 (+) Length   219 a.a.
NCBI ID   WP_024057881.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1882279..1892938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS09235 (ACN076_09235) - 1883082..1884371 (-) 1290 WP_084927218.1 hypothetical protein -
  ACN076_RS09240 (ACN076_09240) - 1885175..1886320 (+) 1146 WP_084927219.1 low temperature requirement protein A -
  ACN076_RS09245 (ACN076_09245) - 1886754..1887209 (-) 456 WP_084927220.1 GNAT family N-acetyltransferase -
  ACN076_RS09250 (ACN076_09250) cclA/cilC 1887279..1887938 (+) 660 WP_024057881.1 prepilin peptidase Machinery gene
  ACN076_RS09255 (ACN076_09255) trpA 1887910..1888686 (-) 777 WP_049516379.1 tryptophan synthase subunit alpha -
  ACN076_RS09260 (ACN076_09260) trpB 1888679..1889902 (-) 1224 WP_004256047.1 tryptophan synthase subunit beta -
  ACN076_RS09265 (ACN076_09265) - 1889880..1890479 (-) 600 WP_020901643.1 phosphoribosylanthranilate isomerase -
  ACN076_RS09270 (ACN076_09270) trpC 1890466..1891233 (-) 768 WP_024057632.1 indole-3-glycerol phosphate synthase TrpC -
  ACN076_RS09275 (ACN076_09275) trpD 1891230..1892234 (-) 1005 WP_033684824.1 anthranilate phosphoribosyltransferase -
  ACN076_RS09280 (ACN076_09280) - 1892245..1892811 (-) 567 WP_153193052.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24822.98 Da        Isoelectric Point: 7.9597

>NTDB_id=1111472 ACN076_RS09250 WP_024057881.1 1887279..1887938(+) (cclA/cilC) [Streptococcus sp. K0074]
MIDFYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKATYPVWYALFELGLG
LLFLAWSWELLSLGQVVLITAGLTLGIYDFRHQEYPLLVWMTFHLILMAGSGWNLVMVFFLVLGIVAHFINIRMGAGDFL
FLASCALVFSVTELLILIQSASAMGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1111472 ACN076_RS09250 WP_024057881.1 1887279..1887938(+) (cclA/cilC) [Streptococcus sp. K0074]
ATGATTGATTTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCTTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCCAACCTGCTAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGCTACATATCCTGTCTGGTATGCCCTTTTTGAATTGGGCTTAGGA
CTCCTCTTTCTGGCTTGGTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTAGTCTGGATGACTTTCCACCTAATCCTAATGGCCGGATCTGGCTGGA
ATCTGGTCATGGTCTTCTTCCTTGTCCTTGGAATTGTGGCTCATTTTATCAATATTCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGTGTAACGGAGTTACTGATCTTGATTCAGTCTGCTTCTGCGATGGGAATTCT
AGCCTTTCTCCTACAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus pneumoniae Rx1

91.781

100

0.918
  cclA/cilC Streptococcus pneumoniae D39

91.781

100

0.918
  cclA/cilC Streptococcus pneumoniae R6

91.781

100

0.918
  cclA/cilC Streptococcus pneumoniae TIGR4

90.411

100

0.904
  cclA/cilC Streptococcus mitis NCTC 12261

89.498

100

0.895

Multiple sequence alignment