Detailed information NTG1111460

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: ACN076_RS07255
• Genome accession: NZ_CP184836
• Coordinates: 1482854..1484188 (-)
• Length: 444 a.a.
• NCBI ID: WP_153193329.1
• Uniprot ID: -
• Organism: Streptococcus sp. K0074
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1477854..1489188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS07250 (ACN076_07250)	-	1479054..1482596 (-)	3543	WP_420789708.1	pneumococcal-type histidine triad protein	-
ACN076_RS07255 (ACN076_07255)	ciaH	1482854..1484188 (-)	1335	WP_153193329.1	two-component system sensor histidine kinase CiaH	Regulator
ACN076_RS07260 (ACN076_07260)	ciaR	1484178..1484852 (-)	675	WP_060805708.1	two-component system response regulator CiaR	Regulator
ACN076_RS07265 (ACN076_07265)	-	1484961..1487507 (-)	2547	WP_261219218.1	M1 family metallopeptidase	-
ACN076_RS07270 (ACN076_07270)	-	1487629..1488069 (-)	441	WP_101782032.1	ASCH domain-containing protein	-
ACN076_RS07275 (ACN076_07275)	-	1488029..1488913 (-)	885	WP_261023939.1	putative PEP-binding protein	-

Sequence

Protein

• Length: 444 a.a.
• Molecular weight: 50718.44 Da
• Isoelectric Point: 9.1616

>NTDB_id=1111460 ACN076_RS07255 WP_153193329.1 1482854..1484188(-) (ciaH) [Streptococcus sp. K0074]
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHGLSENPQAVIQLAVNRATEEIKDLENAA
TDTSKTEVKPNVSSNTEVILFDKNFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRMILMETNISSVSTN
IKYAAILINTSQLEQASQKHEKLIVIVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENDRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGVGISTEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTITVKDNKPKGTIFEVKIAIHTPSKKKK

Nucleotide

• Length: 1335 bp

>NTDB_id=1111460 ACN076_RS07255 WP_153193329.1 1482854..1484188(-) (ciaH) [Streptococcus sp. K0074]
ATGTTCAGTAAACTAAAAAAAACATGGTATGCGGATGACTTTAGTTATTTTATCCGTAACTTTGGTGTCTTCACTCTGAT
TTTCTCCACCATGACTCTGATTATTTTGCAGGTCATGCACTCGAGTCTCTATACTTCGGTGGATGATAAGCTTCATGGAC
TGAGTGAAAATCCTCAGGCAGTTATTCAGCTTGCGGTAAATAGGGCAACTGAAGAGATTAAAGACTTAGAGAATGCCGCT
ACAGATACTAGCAAGACTGAGGTAAAACCCAATGTCAGTTCCAATACGGAGGTTATTCTTTTTGATAAAAATTTTACCCA
ACTCCTTTCTGGAAATCGATTTTTGGGATTGGATAAGATTAAGTTAGAAAAGAAAGAATTAGGCCATATCTACCAGATTC
AGGTTTTTAATAGCTATGGACAGGAAGAAATCTATCGCATGATTTTGATGGAAACGAATATCAGTTCGGTTTCAACCAAT
ATCAAGTATGCAGCTATCTTGATTAATACCAGTCAGTTGGAGCAGGCCAGTCAAAAGCACGAGAAATTGATTGTGATTGT
GATGGCAAGTTTCTGGATTTTATCTTTACTTGCAAGTCTCTATCTAGCTAGGGTCAGTGTTAGGCCCCTGCTTGAGAGCA
TGCAGAAGCAACAGTCCTTTGTGGAAAATGCTAGTCATGAGTTACGAACTCCACTCGCAGTTTTGCAAAATCGCTTAGAG
ACCCTTTTTCGTAAGCCAGAAGCAACCATTATGGATGTGAGCGAAAGCATTGCCTCTAGTTTGGAAGAAGTCCGAAATAT
GCGGTTTTTGACGACGAACTTGTTGAATTTAGCTCGTAGAGATGATGGGATTAAGCCGGAACTTGCAGAAGTTCCAACCA
GTTTTTTCAATACGACTTTCACAAACTATGAAATGATTGCTTCGGAAAATGATCGTGTCTTCCGTTTTGAAAATCGGATT
CATCGAACGATTGTCACAGATCAGCTTCTTTTGAAACAACTGATGACCATCTTATTTGATAATGCTGTCAAGTATACTGA
AGAGGATGGTGAAATTGATTTTCTTATCTCGGCGACTGATCGCAATCTGTATTTACTTGTTTCTGATAATGGAGTCGGTA
TTTCCACAGAAGATAAGAAGAAAATTTTTGATCGCTTTTATCGAGTGGACAAGGCTAGAACCCGCCAAAAAGGTGGTTTT
GGTTTAGGGTTATCCCTAGCCAAGCAAATTGTAGATGCCTTAAAAGGAACCATTACTGTCAAAGATAATAAACCGAAAGG
AACAATCTTTGAAGTGAAGATTGCTATCCACACACCATCTAAAAAGAAAAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (217-283)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (327-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus pneumoniae Rx1	96.396	100	0.964
ciaH	Streptococcus pneumoniae D39	96.396	100	0.964
ciaH	Streptococcus pneumoniae R6	96.396	100	0.964
ciaH	Streptococcus pneumoniae TIGR4	96.396	100	0.964
ciaH	Streptococcus mutans UA159	55.862	97.973	0.547